2-(2-Aminophenyl)ethanol

2-(2-Aminophenyl)ethanol Structure
2-(2-Aminophenyl)ethanol structure
Common Name 2-(2-Aminophenyl)ethanol
CAS Number 5339-85-5 Molecular Weight 137.179
Density 1.1±0.1 g/cm3 Boiling Point 306.7±0.0 °C at 760 mmHg
Molecular Formula C8H11NO Melting Point 89ºC
MSDS USA Flash Point 127.9±20.4 °C
Symbol GHS07
GHS07
Signal Word Warning

Ruthenium-catalyzed dehydrogenative N-heterocyclization. Indoles from 2-aminophenethyl alcohols and 2-nitrophenethyl alcohols. Tsuji Y, et al.

J. Org. Chem. 55(2) , 580-84, (1990)

N-(Cyanothioformyl) indoline; a new indoline ring forming reaction. Besson T, et al.

J. Chem. Soc. Perkin Trans. I 24 , 4057-60, (1998)

One-pot cyclization of 2-aminophenethyl alcohols: a novel and direct approach to the synthesis of N-acyl indolines.

J. Org. Chem. 72(24) , 9364-7, (2007)

A unique one-pot cyclization of 2-aminophenethyl alcohols with carboxylic acids in the presence of PPh3, CCl4, and NEt3 furnished the formation of N-acyl indolines in good to excellent yields. This new approach provides an efficient, scalable, low-cost, and d...