Betahistine Mesylate

Betahistine Mesylate Structure
Betahistine Mesylate structure
Common Name Betahistine Mesylate
CAS Number 54856-23-4 Molecular Weight 328.406
Density N/A Boiling Point 210.9ºC at 760 mmHg
Molecular Formula C10H20N2O6S2 Melting Point 112°C
MSDS N/A Flash Point 96.7ºC

Comparison of the therapeutic efficacy of a fixed low-dose combination of cinnarizine and dimenhydrinate with betahistine in vestibular neuritis: a randomized, double-blind, non-inferiority study.

Clin. Drug Investig. 32(6) , 387-99, (2012)

Vestibular neuritis (VN) is a strongly disabling disease of the peripheral vestibular system. Rapid and effective relief of symptoms is important to allow patients to promptly return to normal physical activity.The aim of this prospective, randomized, double-...

Betahistine or Cinnarizine for treatment of Meniere's disease.

Med. Arh. 66(6) , 396-8, (2012)

Meniere's disease is a condition with sudden attacks of vertigo with nausea and vomiting accompanied by loss of hearing and buzzing sensation in the ears, most commonly unilateral. The exact cause of the disease is unknown. Betahistine is the analogue of hist...

Vestibular rehabilitation with virtual reality in Ménière's disease.

Braz. J. Otorhinolaryngol. 79(3) , 366-74, (2013)

Virtual reality technology can provide a wide range of sensory stimuli to generate conflicts of varying degrees of complexity in a safe environment.To verify the effect of a virtual realitybased balance rehabilitation program for patients with Menière's disea...

Menière-like syndrome in Camurati-Engelmann disease.

Isr. Med. Assoc. J. 15(7) , 390-1, (2013)

Benign paroxysmal positional vertigo (BPPV): influence of pharmacotherapy and rehabilitation therapy on patients' recovery rate and life quality.

NeuroRehabilitation 31(4) , 435-41, (2012)

This prospective clinical study includes 96 BPPV patients with the results of DHI testing ≥ 40 points. They were segregated to be taken into this study and randomly divided into two therapy groups: 48 patients in Group I were treated pharmacotherapeutically w...

Bayesian model selection techniques as decision support for shaping a statistical analysis plan of a clinical trial: an example from a vertigo phase III study with longitudinal count data as primary endpoint.

BMC Med. Res. Methodol. 12 , 137, (2012)

A statistical analysis plan (SAP) is a critical link between how a clinical trial is conducted and the clinical study report. To secure objective study results, regulatory bodies expect that the SAP will meet requirements in pre-specifying inferential analyse...

Involvement of histamine receptors in SAPK/JNK phosphorylation

Int. Immunopharmacol. 13(2) , 190-6, (2012)

Histamine is a mediator of inflammation in allergic disease and asthma. Stress activated protein kinases/c-jun N-terminal kinases (SAPK/JNK) are involved in asthma. This study examined the role of histamine receptors on the phosphorylation of SAPK/JNK in sple...

[Treatment of vestibular vertigo and Ménière syndrome in outpatient clinics].

Zh. Nevrol. Psikhiatr. Im. S. S. Korsakova 112(12) , 36-40, (2012)

An aim of this study was to assess clinical efficacy and tolerability of tagista in the symptomatic treatment of vestibular vertigo and Ménière syndrome. Thirty-two patients, 16 women and 16 men, aged from 25 to 67 years, were examined. Vertigo was caused by ...

[Efficacy of vestibo in the treatment of vertebrobasilar insufficiency].

Zh. Nevrol. Psikhiatr. Im. S. S. Korsakova 112(4) , 53-6, (2012)

Histamine and antipsychotic drug-induced weight gain.

J. Psychopharmacol. 26(12) , 1608-9, (2012)