4-Bromo-2-fluorobenzonitrile
4-Bromo-2-fluorobenzonitrile structure
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Common Name | 4-Bromo-2-fluorobenzonitrile | ||
|---|---|---|---|---|
| CAS Number | 105942-08-3 | Molecular Weight | 200.008 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 231.8±20.0 °C at 760 mmHg | |
| Molecular Formula | C7H3BrFN | Melting Point | 69-72 °C | |
| MSDS | Chinese USA | Flash Point | 94.0±21.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors.
Bioorg. Med. Chem. 14(20) , 6832-46, (2006) A series of heteroaryl-pyridine containing inhibitors of Akt are reported. The synthesis and structure-activity relationships are discussed, leading to the discovery of a indazole-pyridine analogue (K(i)=0.16 nM). These compounds bind in the ATP binding site,... |
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Application of aryloximes as solid-phase ketone linkers.
Org. Lett. 5(1) , 7-10, (2003) In both solution and the solid phase, a variety of ketone oxime anions have been treated with 4-substituted-2-fluorobenzonitriles to give the corresponding nucleophilic aromatic substitution aryloxime adducts. Under aqueous acidic conditions, these adducts un... |
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