2,4,6-Trifluorophenol

2,4,6-Trifluorophenol Structure
2,4,6-Trifluorophenol structure
Common Name 2,4,6-Trifluorophenol
CAS Number 2268-17-9 Molecular Weight 148.083
Density 1.5±0.1 g/cm3 Boiling Point 128.1±35.0 °C at 760 mmHg
Molecular Formula C6H3F3O Melting Point 49-51 °C(lit.)
MSDS Chinese USA Flash Point 55.1±20.4 °C
Symbol GHS07
GHS07
Signal Word Warning

Synthesis and evaluation of 3-aryloxymethyl-1,2-dimethylindole-4,7-diones as mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1) activity.

J. Med. Chem. 50 , 5780-9, (2007)

NAD(P)H:quinone oxidoreductase 1 is a proposed target in pancreatic cancer. We describe the synthesis of a series of indolequinones, based on the 5- and 6-methoxy-1,2-dimethylindole-4,7-dione chromophores with a range of phenolic leaving groups at the (indol-...

Binding of phenol and differently halogenated phenols to dissolved humic matter as measured by NMR spectroscopy.

Environ. Sci. Technol. 43(14) , 5377-82, (2009)

1H- and 19F-NMR measurements of spin-lattice (T1) and spin-spin (T2) relaxationtimes and diffusion ordered spectroscopy (DOSY) were applied to investigate the association of nonsubstituted (phenol (P)) and halogen-substituted (2,4-dichlorophenol (DCP); 2,4,6-...

Development and evaluation of an immunoassay for biological monitoring chlorophenols in urine as potential indicators of occupational exposure.

Anal. Chem. 74(2) , 468-78, (2002)

Trichlorophenols (TCP) eliminated by the urine can be considered as potential biomarkers of exposure of many chemicals (chlorophenols, chlorophenoxy acid herbicides, prochloraz, lindane, hexachlorobenzene, etc). High-throughput screening methods are necessary...

Revisiting the peroxidase oxidation of 2,4,6-trihalophenols: ESR detection of radical intermediates.

Chem. Res. Toxicol. 24(11) , 1862-8, (2011)

The peroxidase oxidation of 2,4,6-trichlorophenol (TCP) has been clearly shown to result in 2,6-dichloro-1,4-benzoquinone (DCQ). DCQ is a 2-electron oxidation product of TCP that has undergone para dechlorination. Many peroxidases show similar oxidation of th...