methyl 4-nitrobutyrate

methyl 4-nitrobutyrate Structure
methyl 4-nitrobutyrate structure
Common Name methyl 4-nitrobutyrate
CAS Number 13013-02-0 Molecular Weight 147.12900
Density 1.155g/cm3 Boiling Point 238.5ºC at 760mmHg
Molecular Formula C5H9NO4 Melting Point N/A
MSDS Chinese USA Flash Point 107.3ºC

Enantioselective Henry addition of methyl 4-nitrobutyrate to aldehydes. Chiral building blocks for 2-pyrrolidinones and other derivatives.

Org. Lett. 12(13) , 3058-61, (2010)

A catalytic highly enantioselective Henry addition of methyl 4-nitrobutyrate to aldehydes using a Cu(II)-amino pyridine complex as catalyst is described. The products resulting from this reaction constitute a new, highly versatile family of chiral building bl...