Oxolamine (citrate)

Oxolamine (citrate) Structure
Oxolamine (citrate) structure
Common Name Oxolamine (citrate)
CAS Number 1949-20-8 Molecular Weight 437.44400
Density 1.066g/cm3 Boiling Point 364.8ºC at 760 mmHg
Molecular Formula C20H27N3O8 Melting Point 153-154ºC
MSDS Chinese USA Flash Point 174.4ºC
Symbol GHS07
GHS07
Signal Word Warning

[Therapeutic action of oxolamine in acute tracheo-bronchitis].

Clin. Ter. 100(5) , 485-92, (1982)

Hallucinations in children caused by oxolamine citrate.

Med. J. Aust. 150(8) , 449-50, 452, (1989)

Twenty reports in Australia, Belgium and The Netherlands have implicated oxolamine-citrate cough-mixtures as a cause of hallucinations in children of less than 10 years of age. Fever is not thought to be a likely alternative explanation. Similar reactions in ...

Sustained-release dosage form of oxolamine citrate: preparation and release kinetics.

J. Microencapsul. 9(2) , 167-72, (1992)

One of the principal uses of microencapsulation for pharmaceuticals has been the preparation of sustained-release dosage forms which have been usually presented in the form of a suspension or gel. However, a non-disintegrating tablet would be a better formula...

Effect of oxolamine on cough sensitivity in COPD patients.

Respir. Med. 96(1) , 61-3, (2002)

Gender difference in the pharmacokinetic interaction between oral warfarin and oxolamine in rats: inhibition of CYP2B1 by oxolamine in male rats.

Biopharm. Drug Dispos. 28(3) , 125-33, (2007)

The possible reason for the significantly greater AUC of oral warfarin with oral oxolamine in male Sprague-Dawley rats was evaluated. After oral administration of warfarin at a dose of 2 mg/kg to male rats with oxolamine at doses of 10 and 50 mg/kg, the AUC v...

[The use of guacetisal in chronic obstructive bronchopneumopathy. Controlled clinical study].

Minerva Med. 72(7) , 355-62, (1981)

A single-blind, between-patients trial was run to compare the fluidifying, expectorant, antitussive, antipyretic and anti-inflammatory activity, and the local and systemic tolerance of guacetisal, an active principle obtained by the esterification of acetylsa...