meprobamate
meprobamate structure
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Common Name | meprobamate | ||
|---|---|---|---|---|
| CAS Number | 57-53-4 | Molecular Weight | 218.250 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 434.2±28.0 °C at 760 mmHg | |
| Molecular Formula | C9H18N2O4 | Melting Point | 104 - 106ºC | |
| MSDS | Chinese USA | Flash Point | 229.7±20.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Nerve demyelination increases metabotropic glutamate receptor subtype 5 expression in peripheral painful mononeuropathy.
Int. J. Mol. Sci. 16(3) , 4642-65, (2015) Wallerian degeneration or nerve demyelination, arising from spinal nerve compression, is thought to bring on chronic neuropathic pain. The widely distributed metabotropic glutamate receptor subtype 5 (mGluR5) is involved in modulating nociceptive transmission... |
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Vestibular dysfunction, altered macular structure and trait localization in A/J inbred mice.
Mamm. Genome 26(3-4) , 154-72, (2015) A/J mice develop progressive hearing loss that begins before 1 month of age and is attributed to cochlear hair cell degeneration. Screening tests indicated that this strain also develops early onset vestibular dysfunction and has otoconial deficits. The purpo... |
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Effect of acute asenapine treatment on Fos expression in the forebrain structures under normal conditions and mild stress preconditioning in the rat.
Brain Res. Bull. 108 , 60-6, (2014) Asenapine (ASE) is a novel atypical antipsychotic drug approved for the treatment of schizophrenia and bipolar disorder. Stress is an inseparable part of the human life, which may interfere with the therapeutic effect of different drugs. The aim of the presen... |
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Cell protrusions induced by hyaluronan synthase 3 (HAS3) resemble mesothelial microvilli and share cytoskeletal features of filopodia.
Exp. Cell Res. 337 , 179-91, (2015) Previous studies have shown that overexpression of enzymatically active GFP-HAS induces the growth of long, slender protrusions that share many features of both filopodia and microvilli. These protrusions are dependent on continuing hyaluronan synthesis, and ... |
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Enhancing the speed of morpholino-DNA biosensor by electrokinetic concentration of DNA in a microfluidic chip.
Biosens. Bioelectron. 72 , 87-94, (2015) Electrokinetic methods that conveniently concentrate charged analytes by orders of magnitude are highly attractive for nucleic acid assays where they can bypass the complexity and costs of enzyme-based amplification. The present study demonstrates an electrok... |
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Differential expression patterns of K(+) /Cl(-) cotransporter 2 in neurons within the superficial spinal dorsal horn of rats.
J. Comp. Neurol. 523 , 1967-83, (2015) γ-Aminobutyric acid (GABA)- and glycine-mediated hyperpolarizing inhibition is associated with a chloride influx that depends on the inwardly directed chloride electrochemical gradient. In neurons, the extrusion of chloride from the cytosol primarily depends ... |
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Microglial response to Alzheimer's disease is differentially modulated by voluntary wheel running and enriched environments.
Brain Struct. Funct. 220(2) , 941-53, (2015) Alzheimer's disease (AD) is an untreatable neurodegenerative disease that deteriorates memory. Increased physical/cognitive activity reduces dementia risk by promoting neuronal and glial response. Although few studies have investigated microglial response in ... |
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Carrier Mediated Distribution System (CAMDIS): a new approach for the measurement of octanol/water distribution coefficients.
Eur. J. Pharm. Sci. 68 , 68-77, (2015) Here we present a miniaturized assay, referred to as Carrier-Mediated Distribution System (CAMDIS) for fast and reliable measurement of octanol/water distribution coefficients, log D(oct). By introducing a filter support for octanol, phase separation from wat... |
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CYP-independent inhibition of platelet aggregation in rabbits by a mixed disulfide conjugate of clopidogrel.
Thromb. Haemost. 112(6) , 1304-11, (2014) Dual antiplatelet therapy with clopidogrel and aspirin has been the standard of care in the United States for patients with acute coronary syndromes (ACS) and/or undergoing percutaneous coronary interventions (PCI). However, the effectiveness of clopidogrel v... |
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Determination and separation of bisphenol A, phthalate metabolites and structural isomers of parabens in human urine with conventional high-pressure liquid chromatography combined with electrospray ionisation tandem mass spectrometry.
Anal. Bioanal. Chem 407(9) , 2509-18, (2015) Phthalates, bisphenol A (BPA) and parabens (PBs), organic chemicals widely used in everyday products, are considered to be endocrine disruptors. We propose a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of seven phtha... |