Fmoc-Pro-OH

Fmoc-Pro-OH Structure
Fmoc-Pro-OH structure
Common Name Fmoc-Pro-OH
CAS Number 71989-31-6 Molecular Weight 337.369
Density 1.3±0.1 g/cm3 Boiling Point 548.6±43.0 °C at 760 mmHg
Molecular Formula C20H19NO4 Melting Point 112-115ºC
MSDS Chinese USA Flash Point 285.6±28.2 °C

Metabolomic serum profiling detects early-stage high-grade serous ovarian cancer in a mouse model.

J. Proteome Res. 14(2) , 917-27, (2015)

Ovarian cancer is a deadly disease killing more than any other gynecologic cancer. Nonspecific symptoms, combined with a lack of early detection methods, contribute to late diagnosis and low five-year survival rates. High-grade serous carcinoma (HGSC) is the ...

Non-covalent photo-patterning of gelatin matrices using caged collagen mimetic peptides.

Macromol. Biosci. 15(1) , 52-62, (2015)

To address the downside of conventional photo-patterning which can alter the chemical composition of protein scaffolds, we developed a non-covalent photo-patterning strategy for gelatin (denatured collagen) hydrogels that utilizes UV activated triple helical ...

Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction.

J. Med. Chem. 53 , 2215-26, (2010)

We report the molecular design and synthesis of EG00229, 2, the first small molecule ligand for the VEGF-A receptor neuropilin 1 (NRP1) and the structural characterization of NRP1-ligand complexes by NMR spectroscopy and X-ray crystallography. Mutagenesis stu...

Cell-penetrating apoptotic peptide/p53 DNA nanocomplex as adjuvant therapy for drug-resistant breast cancer.

Mol. Pharm. 11(10) , 3352-60, (2014)

Drug resistance becomes a formidable challenge against effective cancer therapy. Defective apoptosis in cancer cells is a key factor responsible for chemoresistance or radioresistance. Promoting apoptosis is an important method to sensitize the resistant cell...

Complete ON/OFF photoswitching of the motility of a nanobiomolecular machine.

ACS Nano 8(5) , 4157-65, (2014)

To apply motor proteins as natural nanomolecular machines to transporting systems in nanotechnology, complete temporal control over ON/OFF switching of the motility is necessary. We have studied the photoresponsive inhibition properties of azobenzene-tethered...

Synergistic antibacterial and anti-inflammatory activity of temporin A and modified temporin B in vivo.

PLoS ONE 4 , e7191, (2009)

Temporins are antimicrobial peptides secreted by the granular glands of the European red frog (Rana temporaria). They are 10-14 amino acid long polypeptides active prevalently against gram positive bacteria. This study shows that a synthetic temporin B analog...

Gas-phase fragmentation of oligoproline peptide ions lacking easily mobilizable protons.

J. Am. Soc. Mass Spectrom. 24 , 846-56, (2013)

The fragmentation of peptides containing quaternary ammonium group, but lacking easily mobilizable protons, was examined with the aid of deuterium-labeled analogs and quantum-chemical modeling. The fragmentation of oligoproline containing quaternary ammonium ...