Sodium chromate anhydrous

Sodium chromate anhydrous Structure
Sodium chromate anhydrous structure
Common Name Sodium chromate anhydrous
CAS Number 7775-11-3 Molecular Weight 161.97300
Density 1.483 Boiling Point 392ºC
Molecular Formula CrNa2O4 Melting Point 792ºC
MSDS Chinese USA Flash Point N/A
Symbol GHS05 GHS06 GHS08 GHS09
GHS05, GHS06, GHS08, GHS09
Signal Word Danger

Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions.

J. Immunol. 194 , 5497-508, (2015)

Engineering of the constant Fc part of monoclonal human IgG1 (hIgG1) Abs is an approach to improve effector functions and clinical efficacy of next-generation IgG1-based therapeutics. A main focus in such development is tailoring of in vivo half-life and tran...

Human Skin Cells Are More Sensitive than Human Lung Cells to the Cytotoxic and Cell Cycle Arresting Impacts of Particulate and Soluble Hexavalent Chromium.

Biol. Trace Elem. Res. 166 , 49-56, (2015)

Hexavalent chromium Cr(VI) is a known human lung carcinogen, with solubility playing an important role in its carcinogenic potency. Dermal exposure to Cr(VI) is common and has been associated with skin damage; however, no link between chromate exposure and sk...

Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs.

J. Immunol. 194(1) , 463-74, (2014)

Fluorochrome-conjugated peptide-MHC (pMHC) multimers are commonly used in combination with flow cytometry for direct ex vivo visualization and characterization of Ag-specific T cells, but these reagents can fail to stain cells when TCR affinity and/or TCR cel...

Inhibition of CD39 enzymatic function at the surface of tumor cells alleviates their immunosuppressive activity.

Cancer. Immunol. Res. 3(3) , 254-65, (2015)

The ectonucleotidases CD39 and CD73 hydrolyze extracellular adenosine triphosphate (ATP) and adenosine diphosphate (ADP) to generate adenosine, which binds to adenosine receptors and inhibits T-cell and natural killer (NK)-cell responses, thereby suppressing ...

The regulatory T cell effector molecule fibrinogen-like protein 2 is necessary for the development of rapamycin-induced tolerance to fully MHC-mismatched murine cardiac allografts.

Immunology 144(1) , 91-106, (2015)

Therapies that promote tolerance in solid organ transplantation will improve patient outcomes by eliminating the need for long-term immunosuppression. To investigate mechanisms of rapamycin-induced tolerance, C3H/HeJ mice were heterotopically transplanted wit...

Particulate and soluble hexavalent chromium are cytotoxic and genotoxic to human lung epithelial cells.

Mutat. Res. 610(1-2) , 2-7, (2006)

Particulate hexavalent chromium (Cr(VI)) is a well-established human lung carcinogen. It is currently a major public health concern, there is widespread exposure to it in occupational settings and to the general public. However, despite the potential widespre...

Cytotoxicity and genotoxicity of hexavalent chromium in human and North Atlantic right whale (Eubalaena glacialis) lung cells

Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 150(4) , 487-94, (2009)

Humans and cetaceans are exposed to a wide range of contaminants. In this study, we compared the cytotoxic and genotoxic effects of a metal pollutant, hexavalent chromium [Cr(VI)], which has been shown to cause damage in lung cells from both humans and North ...

The clastogenic effects of chronic exposure to particulate and soluble Cr(VI) in human lung cells.

Mutat. Res. 610(1-2) , 8-13, (2006)

Hexavalent chromium (Cr(VI)) is a well-designated human lung carcinogen, with solubility playing an important role in its carcinogenic potential. Although it is known that particulate or water-insoluble Cr(VI) compounds are more potent than the soluble specie...

Human lung cell growth is not stimulated by lead ions after lead chromate-induced genotoxicity.

Mol. Cell Biochem. 279(1-2) , 75-84, (2005)

Chromate compounds are known human lung carcinogens. Water solubility is an important factor in the carcinogenicity of these compounds with the most potent carcinogenic compounds being water-insoluble or 'particulate'. Previously we have shown that particulat...

Comparative cytotoxicity and genotoxicity of particulate and soluble hexavalent chromium in human and sperm whale (Physeter macrocephalus) skin cells.

Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 155(1) , 143-50, (2012)

Chromium (Cr) is a global marine pollutant, present in marine mammal tissues. Hexavalent chromium [Cr(VI)] is a known human carcinogen. In this study, we compare the cytotoxic and clastogenic effects of Cr(VI) in human (Homo sapiens) and sperm whale (Physeter...