3-Aminopyrazole
3-Aminopyrazole structure
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Common Name | 3-Aminopyrazole | ||
|---|---|---|---|---|
| CAS Number | 1820-80-0 | Molecular Weight | 83.092 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 334.5±15.0 °C at 760 mmHg | |
| Molecular Formula | C3H5N3 | Melting Point | 34-37 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 182.6±7.6 °C | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Trypanotoxic activity of thiosemicarbazone iron chelators.
Exp. Parasitol. 150 , 7-12, (2015) Only a few drugs are available for treating sleeping sickness and nagana disease; parasitic infections caused by protozoans of the genus Trypanosoma in sub-Saharan Africa. There is an urgent need for the development of new medicines for chemotherapy of these ... |
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Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer.
Cancer Res. 75 , 2863-74, (2015) Generalized strategies to improve breast cancer treatment remain of interest to develop. In this study, we offer preclinical evidence of an important metabolic mechanism underlying the antitumor activity of inhibitors of the vacuolar-type ATPase (V-ATPase), a... |
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Analysis of gait in rats with olivocerebellar lesions and ability of the nicotinic acetylcholine receptor agonist varenicline to attenuate impairments.
Behav. Brain Res. 291 , 342-50, (2015) Studies have demonstrated that administration of the neuronal nicotinic receptor agonist varenicline to rats with olivocerebellar lesions attenuates balance deficits on a rotorod and balance beam, but the effects of this drug on gait deficits have not been in... |
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Identification of ribonucleotide reductase M2 as a potential target for pro-senescence therapy in epithelial ovarian cancer.
Cell Cycle 13(2) , 199-207, (2014) Epithelial ovarian cancer (EOC) is the leading cause of gynecological-related cancer deaths in the United States. There is, therefore, an urgent need to develop novel therapeutic strategies for this devastating disease. Cellular senescence is a state of stabl... |
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Adenosine cyclic 3',5',-monophosphate phosphodiesterasr inhibitors. 2.3-Substituted 5,7-dialkylpyrazolo [1,5-a]pyrimidines.
J. Med. Chem. 18(5) , 460-4, (1975) A number of 3-bromo-, 3-nitro-, and 3-ethoxycarbonyl-5,7-dialkylpyrazolo[1,5-a]pyrimidines were synthesized and screened as in vitro cAMP phosphodiesterase inhibitors. The condensation of 3-aminopyrazole with symmetrical beta-diketones (acetylacetone, heptane... |
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Trends Heterocycl. Chem. 2 , 97, (1991)
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Tetrahedron Lett. 47 , 2611, (2006)
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The interaction of ferrocenoyl peptides with 3-aminopyrazole. Saweczko P and Kraatz H-B.
Coord. Chem. Rev. 190 , 185-98, (1999)
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Synthesis and structure of some 3, 4-annelated coumarin systems. Govori S, et al.
Heterocycl. Comm. 8(2) , 129-34, (2002)
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