4-Methoxysalicylic acid

4-Methoxysalicylic acid Structure
4-Methoxysalicylic acid structure
Common Name 4-Methoxysalicylic acid
CAS Number 2237-36-7 Molecular Weight 168.147
Density 1.4±0.1 g/cm3 Boiling Point 328.7±27.0 °C at 760 mmHg
Molecular Formula C8H8O4 Melting Point 158-159 °C(lit.)
MSDS Chinese USA Flash Point 137.9±17.2 °C
Symbol GHS07
GHS07
Signal Word Warning

Discovery of protein disulfide isomerase P5 inhibitors that reduce the secretion of MICA from cancer cells.

ChemBioChem. 15(11) , 1599-606, (2014)

In order to regulate the activity of P5, which is a member of the protein disulfide isomerase family, we screened a chemical compound library for P5-specific inhibitors, and identified two candidate compounds (anacardic acid and NSC74859). Interestingly, anac...

Inhibition of Cancer Cell Proliferation and Antiradical Effects of Decoction, Hydroalcoholic Extract, and Principal Constituents of Hemidesmus indicus R. Br.

Phytother Res. 29 , 857-63, (2015)

Indian Sarsaparilla (Hemidesmus indicus R. Br.) is widely used in Indian traditional medicine. In the present work, we explored the effects of decoction, traditional Ayurvedic preparation, and hydroalcoholic extract, a phytocomplex more traditionally studied ...

Synthesis, biological evaluation and molecular docking studies of 1,3,4-oxadiazole derivatives as potential immunosuppressive agents.

Bioorg. Med. Chem. 20(10) , 3359-67, (2012)

A series of 1,3,4-oxadiazole derivatives derived from 4-methoxysalicylic acid or 4-methylsalicylic acid (6a-6z) have been first synthesized for their potential immunosuppressive activity. Among them, compound 6z displayed the most potent biological activity a...