Lansoprazole
Lansoprazole structure
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Common Name | Lansoprazole | ||
|---|---|---|---|---|
| CAS Number | 103577-45-3 | Molecular Weight | 369.362 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 555.8±60.0 °C at 760 mmHg | |
| Molecular Formula | C16H14F3N3O2S | Melting Point | 178-182°C dec. | |
| MSDS | Chinese USA | Flash Point | 289.9±32.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Solvent-free melting techniques for the preparation of lipid-based solid oral formulations.
Pharm. Res. 32(5) , 1519-45, (2015) Lipid excipients are applied for numerous purposes such as taste masking, controlled release, improvement of swallowability and moisture protection. Several melting techniques have evolved in the last decades. Common examples are melt coating, melt granulatio... |
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Preventing metachronous gastric lesions after endoscopic submucosal dissection through Helicobacter pylori eradication.
J. Gastroenterol. Hepatol. 30(1) , 75-81, (2014) Metachronous recurrence often occurs after endoscopic submucosal dissection for early gastric cancer, and a method for preventing recurrence is unknown. We aimed to identify risk factors for metachronous lesions, and the effects of aspirin use and Helicobacte... |
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Seco-taondiol, an unusual meroterpenoid from the Chilean seaweed Stypopodium flabelliforme and its gastroprotective effect in mouse model.
Mar. Drugs 13 , 1726-38, (2015) Ten known meroterpenoids and the new meroterpenoid 7 were isolated from the Chilean seaweed Stypopodium flabelliforme as their acetylated derivatives. Furthermore, the known metabolite taondiol has been isolated for the first time from this species. The molec... |
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Does the gastroprotective action of a medicinal plant ensure healing effects? An integrative study of the biological effects of Serjania marginata Casar. (Sapindaceae) in rats.
J. Ethnopharmacol. 172 , 312-24, (2015) Serjania marginata (Sapindaceae), a medicinal plant commonly found in the Brazilian Cerrado, Paraguay, Bolivia and Argentina, is also known as "cipó-uva" or "cipó-timbó". Ethnopharmacological studies indicate that the leaves from this medicinal plant are used... |
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Influence of the proton pump inhibitor lansoprazole on distribution and activity of doxorubicin in solid tumors.
Cancer Sci. 106 , 1438-47, (2015) Cellular causes of resistance and limited drug distribution within solid tumors limit therapeutic efficacy of anticancer drugs. Acidic endosomes in cancer cells mediate autophagy, which facilitates survival of stressed cells, and may contribute to drug resist... |
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An unusual mulinane diterpenoid from the Chilean plant Azorella trifurcata (Gaertn) Pers.
Org. Biomol. Chem. 12(33) , 6406-13, (2014) Four new mulinane-type diterpenoids besides the known compounds mulin-11,13-dien-20-oic acid, 13α-hydroxyazorellane, 13β-hydroxyazorellane, mulinolic acid, azorellanol, and mulin-11,13-dien-18-acetoxy-16,20-dioic acid were isolated from the Chilean plant Azor... |
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Ulcer healing and mechanism(s) of action involved in the gastroprotective activity of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus.
BMC Complement Altern. Med. 15 , 391, (2015) Syngonanthus arthrotrichus and Syngonanthus bisulcatus, currently known for Comanthera aciphylla (Bong.) L.R.Parra & Giul. and Comanthera bisulcata (Koern.) L.R. Parra & Giul, popularly known in Brazil as "sempre-vivas," are plants from the family Eriocaulace... |
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Education and imaging. Gastrointestinal: colonic mucosa-associated lymphoid tissue lymphoma regressed by levofloxacin.
J. Gastroenterol. Hepatol. 28(4) , 750, (2013)
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Is the full potential of the biopharmaceutics classification system reached?
Eur. J. Pharm. Sci. 57 , 224-31, (2014) In this paper we analyse how the biopharmaceutics classification system (BCS) has been used to date. A survey of the literature resulted in a compilation of 242 compounds for which BCS classes were reported. Of these, 183 compounds had been reported to belong... |
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In vitro study of the variable effects of proton pump inhibitors on voriconazole.
Antimicrob. Agents Chemother. 59 , 5548-54, (2015) Voriconazole is a broad-spectrum antifungal agent used for the treatment of severe fungal infections. Maintaining therapeutic concentrations of 1 to 5.5 μg/ml is currently recommended to maximize the exposure-response relationship of voriconazole. However, th... |