β-Estradiol-6-one 6-(O-carboxymethyloxime)
β-Estradiol-6-one 6-(O-carboxymethyloxime) structure
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Common Name | β-Estradiol-6-one 6-(O-carboxymethyloxime) | ||
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| CAS Number | 35048-47-6 | Molecular Weight | 359.416 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 572.6±60.0 °C at 760 mmHg | |
| Molecular Formula | C20H25NO5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 300.1±32.9 °C | |
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A convenient homogeneous enzyme immunoassay for estradiol detection.
Biotechnol. Appl. Biochem. 58(1) , 75-82, (2011) A convenient homogeneous enzyme immunoassay for estradiol is described. Unlike heterogeneous immunoassays, which require time-consuming separation steps or expensive automated systems, homogeneous immunoassays, wherein all reagents are freely suspended in bul... |
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Histochemical estrogen receptor assay.
Am. J. Clin. Pathol. 76(3) , 365, (1981)
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Estrogen receptors in human breast cancer. II. Correlation between the histochemical method and biochemical assay.
Virchows Arch.,. B, Cell Pathol. 40(1) , 27-37, (1982) The present study defines criteria for determining the presence of estrogen-receptors in human breast carcinomas demonstrated by a histochemical assay using 17 beta-estradiol-carboxy-methyl-oxim-bovine serum albumen-FITC. The criteria were: 1) the percentage ... |
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Fluorescent cytochemical oestrogen receptor assay: is it valid in breast cancer?
Br. J. Surg. 70(8) , 457-9, (1983) The performance of a fluorescent cytochemical oestrogen receptor (ER) assay has been compared with an established dextran-coated charcoal ER assay in 85 cases of primary breast cancer. Both assays were performed on tissue samples from the same tumour, by inde... |
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Steroid-bovine serum albumin conjugates: molecular characterization and their interaction with androgen and estrogen receptors.
J. Steroid Biochem. 24(5) , 1017-31, (1986) Conjugates of testosterone-3-carboxymethyloxime (T-3-CMO), testosterone-17-hemisuccinate (T-17-HS), 17 beta-estradiol-6-carboxymethyloxime (E-6-CMO), or 17 beta-estradiol-17-hemisuccinate (E-17-HS) and bovine serum albumin (BSA) with varying steroid:protein r... |
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[Impact of calcium channel antagonists for estrogen action on the endometrial carcinoma HEC-1A cells].
Zhonghua Fu Chan Ke Za Zhi 47(3) , 212-7, (2012) To study the effects of nifedipine and mibefradil on the cell proliferation, apoptosis, migration on the HEC-1A in vitro and also study the mRNA and protein expression levels of the calcium channel alpha1D (Cav1.3) and calcium channel alpha1G (Cav3.1) to disc... |
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[Synthesis of receptor reagent--estradiol-polyethyleneglycol-fluorescein isothiocyanate].
Yao Xue Xue Bao 26(5) , 336-40, (1991) Estradiol conjugate has been used as a tracer to detect estrogen receptor of human mammary cancer cells. In order to look for more stable carrier of fluorescent estradiol conjugate, we substituted polyethyleneglycol (PEG) for bovine serum albumin (BSA) and sy... |
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[Synthesis of new test reagents for the estrogen receptor in human breast cancer tissues].
Yao Xue Xue Bao 26(8) , 611-4, (1991) According to the character of structure and activity of the test reagents I-IV, two new reagents V and VI for detecting estrogen receptor of human mammary cancer cells were synthesized. This simplifies the route of synthesis and increases activity. Key interm... |
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Comparison of biochemical and histochemical techniques for estrogen receptor analyses in mammary carcinoma.
Cancer 46(12 Suppl) , 2842-5, (1980) Three histochemical techniques for estrogen binding localization in tissue sections were compared to sucrose density gradient analyses for estrogen receptor in 186 breast carcinomas. Apparent localization to epithelial elements was noted using 6-BSA-Fluor-CMO... |
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Prevention of bridge binding in immunoassays: a general estradiol tracer structure.
J. Steroid Biochem. 32(2) , 251-7, (1989) Iodinated estradiol tracers were synthesized with three different bridges connecting the radiolabelled moiety to the steroid core: Hemisuccinate, carboxymethyloxime and amide. Taking these iodinated tracers in combination with ten antibodies raised against es... |