Cyclopentanone

Cyclopentanone Structure
Cyclopentanone structure
Common Name Cyclopentanone
CAS Number 120-92-3 Molecular Weight 84.116
Density 1.0±0.1 g/cm3 Boiling Point 130.5±8.0 °C at 760 mmHg
Molecular Formula C5H8O Melting Point -51 °C
MSDS Chinese USA Flash Point 30.6±0.0 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

Formation of curcumin nanoparticles by flash nanoprecipitation from emulsions.

J. Colloid. Interface Sci. 434 , 65-70, (2014)

Nanometric particles of a model hydrophobic substance curcumin were prepared by a novel method, namely, flash nanoprecipitation from a coarse oil-in-water emulsion. The method employs turbulent co-mixing of water with curcumin-loaded emulsion using manually-o...

In situ SU-8 silver nanocomposites.

Beilstein J. Nanotechnol. 6 , 1661-5, (2015)

Nanocomposite materials containing metal nanoparticles are of considerable interest in photonics and optoelectronics applications. However, device fabrication of such materials always encounters the challenge of incorporation of preformed nanoparticles into p...

Effective Two-Photon Excited Photodynamic Therapy of Xenograft Tumors Sensitized by Water-Soluble Bis(arylidene)cycloalkanone Photosensitizers.

J. Med. Chem. 58 , 7949-58, (2015)

A series of bis(arylidene)cycloalkanone photosensitizers modified by polyethylene glycol (PEG) have been studied for two-photon excited photodynamic therapy (2PE-PDT). As compared with their prototype compounds, these PEGylated photosensitizers show enhanced ...

The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes.

J. Immunol. 194(6) , 2776-85, (2015)

Inflammasomes are cytosolic protein complexes that respond to diverse danger signals by activating caspase-1. The sensor components of the inflammasome, often proteins of the nucleotide-binding oligomerization domain-like receptor (NLR) family, detect stress,...

Copolymer-supported heterogeneous organocatalyst for asymmetric aldol addition in aqueous medium.

Org. Biomol. Chem. 10(21) , 4179-85, (2012)

In the current study, a convenient and simple way is presented to synthesize a novel type of supported heterogeneous organocatalyst in 21-81% yield by the copolymerization of 9-amino-9-deoxy-epi-cinchonine organocatalyst with acrylonitrile using AIBN as radic...

Microwave-assisted synthesis of cyclopentanones using the relevant phosphorus ylides.

Comb. Chem. High Throughput Screen 15(4) , 354-7, (2012)

A one-pot synthesis of cyclopentanone derivatives from phosphorus ylide under lab-type microwave assisted methodology was described. The phosphorus ylides were obtained via the reaction of activated acetylenic compounds, ethyl 4-chloroacetoacetate and triphen...

Catalytic and regioselective ring expansion of arylcyclobutanones with trimethylsilyldiazomethane. Ligand-dependent entry to beta-ketosilane or enolsilane adducts.

Org. Lett. 12(16) , 3598-601, (2010)

Divergent reactivity is uncovered in the homologation of arylcyclobutanones with trimethylsilyldiazomethane. With Sc(OTf)(3) as catalyst, enolsilanes are obtained with a high preference for methylene migration. By contrast, Sc(hfac)(3) gives beta-ketosilanes ...

Chiral picolylamines for Michael and aldol reactions: probing substrate boundaries.

Org. Biomol. Chem. 10(46) , 9287-94, (2012)

Here we report on inroads concerning increased substrate breadth via the picolylamine organocatalyst template, a vicinal chiral diamine based on a pyridine-primary amine motif. The addition of cyclohexanone to β-nitrostyrene has many catalyst solutions, but c...

A convergent stereocontrolled total synthesis of (-)-terpestacin.

Org. Biomol. Chem. 10(28) , 5452-5, (2012)

A stereocontrolled total synthesis of (-)-terpestacin has been achieved starting from (R)-(-)-carvone as a chiral pool and (E,E)-farnesol via a highly convergent approach. Thus, (R)-(-)-carvone was transformed into the cyclopentanone segment through a series ...

Synthesis and biological evaluation of novel exo-methylene cyclopentanone tetracyclic diterpenoids as antitumor agents.

Bioorg. Med. Chem. Lett. 21 , 130-2, (2011)

The structure of exo-methylene cyclopentanone, which exists in nature tetracyclic diterpenoids products, has been proved to be an innate group for the treatment of cancer and inflammation. In this letter, four different scaffolds of tetracyclic diterpenoids i...