Chloroacetic anhydride

Chloroacetic anhydride Structure
Chloroacetic anhydride structure
Common Name Chloroacetic anhydride
CAS Number 541-88-8 Molecular Weight 154.567
Density 1.2±0.1 g/cm3 Boiling Point 159.0±20.0 °C at 760 mmHg
Molecular Formula C5H8ClFO2 Melting Point 51 °C
MSDS Chinese USA Flash Point 63.0±10.9 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

Synthesis of 3,3'-bis(sulfonato)-4,4'-bis(chloroacetamido)azobenzene and cysteine cross-linking for photo-control of protein conformation and activity.

Nat. Protoc. 2(2) , 251-8, (2007)

This protocol describes a procedure for the synthesis of 3,3'-bis(sulfonato)-4,4'-bis(chloroacetamido)azobenzene (BSBCA), a water-soluble, thiol-reactive, photo-switchable cross-linker. In addition, a protocol is outlined for installing the cross-linker in an...

Preparation of enantiomerically pure L-7-azatryptophan by an enzymatic method and its application to the development of a fluorimetric activity assay for tryptophanyl-tRNA synthetase.

Anal. Biochem. 252(2) , 260-70, (1997)

The reaction of D,L-7-azatryptophan (D,L-7AW) with tryptophanyl-tRNA synthetase (TrpRS), adenosine triphosphate (ATP), and Mg2+ in the presence of inorganic pyrophosphatase results in the formation of a highly fluorescent l-7AW-adenylate complex. Detection of...

A facile synthesis of 2-methyl-[3,4-di-O-acetyl-6-O-(chloroacetyl)-1,2-dideoxy-alpha-D-glucopyrano]-[2',1':4,5]-2-oxazoline.

Carbohydr. Res. 51(2) , 215-22, (1976)

The use of the chloroacetyl group as a protecting group has been studied for a 2-methylglyco-[2',1':4,5]-2-oxazoline. The reaction of chloroacetyl chloride or chloroacetic anhydride with 2-acetamido-1,3,4-tri-O-acetyl-2-deoxy-beta-D-glucopyranose provided 2-a...