Nadifloxacin

Nadifloxacin Structure
Nadifloxacin structure
Common Name Nadifloxacin
CAS Number 124858-35-1 Molecular Weight 360.379
Density 1.5±0.1 g/cm3 Boiling Point 624.9±55.0 °C at 760 mmHg
Molecular Formula C19H21FN2O4 Melting Point 245-247ºC (dec)
MSDS Chinese USA Flash Point 331.7±31.5 °C

Efficacy and safety of nadifloxacin for bacterial skin infections: results from clinical and post-marketing studies.

Dermatol. Ther. (Heidelb.) 4(2) , 233-48, (2014)

Skin and soft tissue infections involve microbial invasion of the skin and underlying soft tissues and are estimated to affect 7-10% of hospitalized patients worldwide. Nadifloxacin, a topical fluoroquinolone, has been shown to be effective against aerobic Gr...

Green Nail Syndrome (Pseudomonas aeruginosa Nail Infection): Two Cases Successfully Treated with Topical Nadifloxacin, an Acne Medication.

Case Rep. Dermatol. 6(2) , 180-4, (2014)

Green nail syndrome (GNS) caused by Pseudomonas aeruginosa is the most common bacterial nail infection. The treatment of GNS is challenging in many cases and recommendations based on clinical trials are lacking. We report two cases with GNS successfully treat...

Design and evaluation of microemulsion gel system of nadifloxacin.

Indian J. Pharm. Sci. 74(3) , 237-47, (2012)

Topical microemulsion systems for the antiacne agent, nadifloxacin were designed and developed to overcome the problems associated with the cutaneous delivery due to poor water solubility. The solubility of nadifloxacin in oils, surfactants and cosurfactants ...