Ethyl (diethoxyphosphoryl)(fluoro)acetate

Ethyl (diethoxyphosphoryl)(fluoro)acetate Structure
Ethyl (diethoxyphosphoryl)(fluoro)acetate structure
Common Name Ethyl (diethoxyphosphoryl)(fluoro)acetate
CAS Number 2356-16-3 Molecular Weight 242.182
Density 1.2±0.1 g/cm3 Boiling Point 339.5±0.0 °C at 760 mmHg
Molecular Formula C8H16FO5P Melting Point N/A
MSDS Chinese USA Flash Point 73.9±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

Synthesis and gastrointestinal pharmacology of the 4-fluoro analogue of enisoprost.

J. Med. Chem. 30 , 1952, (1987)

A 4-fluoro analogue of enisoprost was prepared and evaluated for gastric antisecretory and mucosal protective activity in animals. The synthesis centered upon cuprate chemistry but also involved a Wittig reaction to produce a cis fluoro olefinic moiety, a fur...