6-Hydroxynicotinic acid
6-Hydroxynicotinic acid structure
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Common Name | 6-Hydroxynicotinic acid | ||
|---|---|---|---|---|
| CAS Number | 5006-66-6 | Molecular Weight | 139.109 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 488.8±30.0 °C at 760 mmHg | |
| Molecular Formula | C6H5NO3 | Melting Point | >300 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 249.4±24.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.
Nature 457(7231) , 910-4, (2009) Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the identification of critical biomarkers for cancer invasion an... |
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Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine.
Kidney Int. 79(11) , 1244-53, (2011) Autosomal dominant polycystic kidney disease (ADPKD) is a frequent cause of kidney failure; however, urinary biomarkers for the disease are lacking. In a step towards identifying such markers, we used multidimensional-multinuclear nuclear magnetic resonance (... |
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Selenium and selenomethionine levels in prostate cancer patients.
Cancer Detect. Prev. 28(1) , 8-16, (2004) Selenium (Se) and selenomethionine (Se-Met) have been identified as potential chemopreventive agents of prostate cancer. Using an assay for the speciation (separation and identification) and quantification of selenoamino acids, Se-Met was profiled in serum an... |
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Urinary unconjugated 5 alpha-androstane-3 alpha, 17 beta-diol in patients with prostatic tumours.
Urol. Res. 10(2) , 81-4, (1982) A sensitive and reliable radioimmunoassay (RIA) for urinary unconjugated 5 alpha-androstane-3 alpha, 17 beta-diol is described. The mean overall recovery of unconjugated 5 alpha-androstane-3 alpha, 17 beta-diol was found to be 57.4%. The sensitivity of the as... |
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Plasma carotenoids, retinol, and tocopherols and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition study.
Am. J. Clin. Nutr. 86(3) , 672-81, (2007) Previous studies suggest that high plasma concentrations of carotenoids, retinol, or tocopherols may reduce the risk of prostate cancer.We aimed to examine the associations between plasma concentrations of 7 carotenoids, retinol, alpha-tocopherol, and gamma-t... |
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Cloning of a novel 6-chloronicotinic acid chlorohydrolase from the newly isolated 6-chloronicotinic acid mineralizing Bradyrhizobiaceae strain SG-6C.
PLoS ONE 7(11) , e51162, (2012) A 6-chloronicotinic acid mineralizing bacterium was isolated from enrichment cultures originating from imidacloprid-contaminated soil samples. This Bradyrhizobiaceae, designated strain SG-6C, hydrolytically dechlorinated 6-chloronicotinic acid to 6-hydroxynic... |
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[Microplate for high throughput screening of 6-hydroxynicotinic acid transforming strains].
Wei Sheng Wu Xue Bao 48(1) , 112-5, (2008) Recently, new insecticides containing 3-chloropyridylmethyl group as a versatile building block have been developed, among which imidachloprid is a promising one. The synthesis of imidachloprid can use 6-Hydroxynicotinic acid, the first intermediate of the ba... |
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[Combination of growing culture transformation and resting cells transformation of Pseudomonas putida NA-1 for production of 6-hydroxynicotinic acid].
Wei Sheng Wu Xue Bao 46(1) , 63-7, (2006) The current technology for microbial hydroxylation of nicotinic acid is a procedure of resting cells transformation. Here it was reported that non-degradation of 6-hydroxynicotinic acid during hydroxylation of nicotinic acid by resting cells was due to existi... |
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Availability of 6-hydroxynicotinic acid for rapid identification of Pseudomonas aeruginosa and Serratia marcescens.
J. Chromatogr. A. 338(1) , 51-9, (1985) Gas chromatography--mass spectrometry has been used to identify specific metabolites produced by Gram-negative bacteria such as Pseudomonas aeruginosa, Serratia marcescens, Klebsiella pneumoniae and Escherichia coli in a defined medium. 6-Hydroxynicotinic aci... |
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(1)H NMR spectroscopy in the diagnosis of Pseudomonas aeruginosa-induced urinary tract infection.
NMR Biomed. 18(5) , 293-9, (2005) The utility of (1)H NMR spectroscopy is suggested and demonstrated for the diagnosis of Pseudomonas aeruginosa in urinary tract infection (UTI). The specific property of P. aeruginosa of metabolizing nicotinic acid to 6-hydroxynicotinic acid (6-OHNA) is explo... |