2-Aminonicotinic acid
2-Aminonicotinic acid structure
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Common Name | 2-Aminonicotinic acid | ||
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| CAS Number | 5345-47-1 | Molecular Weight | 138.124 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 342.3±27.0 °C at 760 mmHg | |
| Molecular Formula | C6H6N2O2 | Melting Point | 295-297 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 160.8±23.7 °C | |
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2-Aminonicotinic acid 1-oxides are chemically stable inhibitors of quinolinic acid synthesis in the mammalian brain: a step toward new antiexcitotoxic agents.
J. Med. Chem. 56(23) , 9482-95, (2013) 3-Hydroxyanthranilic acid 3,4-dioxygenase (3-HAO) is the enzyme responsible for the production of the neurotoxic tryptophan metabolite quinolinic acid (QUIN). Elevated brain levels of QUIN are observed in several neurodegenerative diseases, but pharmacologica... |
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Alkylation activity and molecular properties of two antineoplastic agents that utilise indometacin and a conjugate of aspirin with 2-aminonicotinic acid to transport nitrogen mustard groups.
Drugs R. D. 8(6) , 363-72, (2007) Nitrogen mustard (N-mustard) compounds are considered important anticancer drugs. Various transporting agents have been utilised to carry N-mustard groups including coumarins, amides, polyaromatic molecules and cycloalkyl structures. N-mustards act as bifunct... |
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Molecular structure (monomeric and dimeric structure) and HOMO-LUMO analysis of 2-aminonicotinic acid: a comparison of calculated spectroscopic properties with FT-IR and UV-vis.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 91 , 83-96, (2012) The experimental (UV-vis and FT-IR) and theoretical study of 2-aminonicotinic acid (C(6)H(6)N(2)O(2)) was presented in this work. The ultraviolet absorption spectrum of title molecule that dissolved in ethanol and water were examined in the range of 200-400 n... |
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2-Aminonicotinic acid.
Acta Crystallogr. C 53 ( Pt 10) , 1427-9, (1997) 2-Aminonicotinic acid, C6H6N2O2, crystallized in the centrosymmetric space group P2(1)/c in the zwitterionic form. Intermolecular N--H...O hydrogen bonds with N...O distances of 2.652 (2) and 2.807 (2) A link molecules into two sets of zigzag chains propagati... |
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Chemiluminescence derivatization of methylglyoxal using 2-aminonicotinic acid.
Chem. Pharm. Bull. 48(8) , 1236-8, (2000) To develop a sensitive and selective chemiluminometric method for the determination of methylglyoxal, we used 2-aminonicotinic acid as the chemiluminescence derivatization reagent. 2-Aminonicotinic acid reacts with methylglyoxal in an acidic solution at 37 de... |