Agmatine sulfate
Agmatine sulfate structure
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Common Name | Agmatine sulfate | ||
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| CAS Number | 2482-00-0 | Molecular Weight | 228.270 | |
| Density | N/A | Boiling Point | 281.4ºC at 760 mmHg | |
| Molecular Formula | C5H16N4O4S | Melting Point | 234-238 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 124ºC | |
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Interaction of myo-inositol hexakisphosphate with biogenic and synthetic polyamines.
Org. Biomol. Chem. 13 , 7500-12, (2015) Within all the eukaryotic cells myo-inositol phosphates (InsPs) are an important group of biomolecules that are potentially related to signaling functions. The most abundant member of this family in nature is InsP6 (phytate, L(12-) in its fully deprotonated f... |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Effect of Novel Starter Culture on Reduction of Biogenic Amines, Quality Improvement, and Sensory Properties of Doenjang, a Traditional Korean Soybean Fermented Sauce Variety.
J. Food Sci. 80 , M1794-803, (2015) To select appropriate microorganisms as starter cultures for the reliable and reproducible fermentation of soybean fermented products of Korean Doenjang, various ratios of fungi (Aspergillus oryzae J, Mucor racemosus 15, M. racemosus 42) combined with Bacillu... |
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Binding mechanisms for histamine and agmatine ligands in plasmid deoxyribonucleic acid purifications
J. Chromatogr. A. 1366 , 110-9, (2014) • The versatility of histamine and agmatine ligands in function of binding and elution conditions. • Histamine and agmatine-pDNA multiple interactions depend of salts, ionic strength and pH. • Both ligands showed a biorecognition to the sc pDNA isoform. • The... |
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Pharmaceutical-grade pre-miR-29 purification using an agmatine monolithic support.
J. Chromatogr. A. 1368 , 173-82, (2014) MicroRNA-based therapeutic applications have fostered a growing interest in the development of microRNAs purification processes in order to obtain the final product with high purity degree, good quality and biologically active. The pre-miR-29 deficiency or ov... |
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Agmatine induces Nrf2 and protects against corticosterone effects in hippocampal neuronal cell line.
Mol. Neurobiol. 51 , 1504-19, (2015) Hyperactivation of the hypothalamic-pituitary-adrenal axis is a common finding in major depression; this may lead to increased levels of cortisol, which are known to cause oxidative stress imbalance and apoptotic neuronal cell death, particularly in the hippo... |
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Is agmatine a novel neurotransmitter in brain?
Trends Pharmacol. Sci. 21 , 187-193, (2000) Recent evidence suggests that agmatine, which is an intermediate in polyamine biosynthesis, might be an important neurotransmitter in mammals. Agmatine is synthesized in the brain, stored in synaptic vesicles in regionally selective neurons, accumulated by up... |
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Agmatine: an endogenous clonidine-displacing substance in the brain.
Science 263 , 966, (1994) Clonidine, an antihypertensive drug, binds to alpha 2-adrenergic and imidazoline receptors. The endogenous ligand for imidazoline receptors may be a clonidine-displacing substance, a small molecule isolated from bovine brain. This clonidine-displacing substan... |
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Agmatine selectively blocks the N-methyl-D-aspartate subclass of glutamate receptor channels in rat hippocampal neurons.
J. Pharmacol. Exp. Ther. 288 , 544-549, (1999) We investigated in rat hippocampus neurons whether 4-(aminobutyl)guanidine (agmatine), formed by decarboxylation of L-arginine by arginine decarboxylase and metabolized to urea and putrescine, can modulate the function of N-methyl-D-aspartate (NMDA) receptor ... |
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Agmatine attenuates silica-induced pulmonary fibrosis.
Hum. Exp. Toxicol. 33(6) , 650-60, (2015) There is a large body of evidence that nitric oxide (NO) formation is implicated in mediating silica-induced pulmonary fibrosis. As a reactive free radical, NO may not only contribute to lung parenchymal tissue injury but also has the ability to combine with ... |