Piceatannol

Piceatannol Structure
Piceatannol structure
Common Name Piceatannol
CAS Number 10083-24-6 Molecular Weight 244.243
Density 1.5±0.1 g/cm3 Boiling Point 507.3±38.0 °C at 760 mmHg
Molecular Formula C14H12O4 Melting Point 223-227ºC
MSDS Chinese USA Flash Point 252.2±21.4 °C

A unique mechanism of curcumin inhibition on F1 ATPase

Biochem. Biophys. Res. Commun. 452(4) , 940-4, (2014)

• Polyphenols lowered the rotation rate of F1 ATPase by increasing catalytic dwell. • Curcumin showed different inhibitory mechanism from other polyphenols. • γ subunit carboxyl terminus is not required for curcumin binding. • Curcumin and γ subunit S174F mut...

Antibody-opsonized bacteria evoke an inflammatory dendritic cell phenotype and polyfunctional Th cells by cross-talk between TLRs and FcRs.

J. Immunol. 194(4) , 1856-66, (2015)

During secondary immune responses, Ab-opsonized bacteria are efficiently taken up via FcRs by dendritic cells. We now demonstrate that this process induces cross-talk between FcRs and TLRs, which results in synergistic release of several inflammatory cytokine...

TH2 cells and their cytokines regulate formation and function of lymphatic vessels.

Nat. Commun. 6 , 6196, (2015)

Lymphatic vessels (LVs) are critical for immune surveillance and involved in the pathogenesis of diverse diseases. LV density is increased during inflammation; however, little is known about how the resolution of LVs is controlled in different inflammatory co...

Expression of activated STAT5 in neoplastic mast cells in systemic mastocytosis: subcellular distribution and role of the transforming oncoprotein KIT D816V.

Am. J. Pathol. 175 , 2416-29, (2009)

Recent data suggest that the signal transducer and activator of transcription (STAT)5 contributes to differentiation and growth of mast cells. It has also been described that constitutively phosphorylated STAT5 (pSTAT5) plays a pro-oncogenic role in various m...

Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.

EMBO Mol. Med. 7(3) , 240-58, (2015)

Transplant recipients on calcineurin inhibitors are at high risk of invasive fungal infection. Understanding how calcineurin inhibitors impair fungal immunity is a key priority for defining risk of infection. Here, we show that the calcineurin inhibitor tacro...

Identification of an Endophytic Antifungal Bacterial Strain Isolated from the Rubber Tree and Its Application in the Biological Control of Banana Fusarium Wilt.

J. Nutr. Biochem. 26 , 1379-84, (2015)

Banana Fusarium wilt (also known as Panama disease) is one of the most disastrous plant diseases. Effective control methods are still under exploring. The endophytic bacterial strain ITBB B5-1 was isolated from the rubber tree, and identified as Serratia marc...

MicroRNA-183 increases osteoclastogenesis by repressing heme oxygenase-1.

Bone 81 , 237-46, (2015)

Emerging evidence suggests that microRNAs (miRs) influence skeletal structure by modulating osteoclastogenesis and bone resorption. We have demonstrated previously that the up-regulation of heme oxygenase-1 (HO-1) attenuated osteoclastogenesis in bone marrow-...

β-Glucan-Activated Human B Lymphocytes Participate in Innate Immune Responses by Releasing Proinflammatory Cytokines and Stimulating Neutrophil Chemotaxis.

J. Immunol. 195 , 5318-26, (2015)

B lymphocytes play an essential regulatory role in the adaptive immune response through Ab production during infection. A less known function of B lymphocytes is their ability to respond directly to infectious Ags through stimulation of pattern recognition re...

In vivo support for the new concept of pulmonary blood flow-mediated CO2 gas excretion in the lungs.

Am. J. Physiol. Lung Cell. Mol. Physiol. 308 , L1224-36, (2015)

To further examine the validity of the proposed concept of pulmonary blood flow-dependent CO2 gas excretion in the lungs, we investigated the effects of intramediastinal balloon catheterization-, pulmonary artery catheterization-, or isoprenaline (ISP)-induce...

Syringetin suppresses osteoclastogenesis mediated by osteoblasts in human lung adenocarcinoma.

Oncol. Rep. 34 , 617-26, (2015)

Bone metastasis in lung cancer results in an unfavorable outcome for patients by not only impairing the quality of life, yet also increasing the cancer-related death rates. In the present study, we discuss a novel treatment strategy that may benefit these pat...