Motilin (26-47), human, porcine

Motilin (26-47), human, porcine Structure
Motilin (26-47), human, porcine structure
Common Name Motilin (26-47), human, porcine
CAS Number 52906-92-0 Molecular Weight 2699.05000
Density N/A Boiling Point N/A
Molecular Formula C120H188N34O35S Melting Point N/A
MSDS Chinese USA Flash Point N/A

Heterotrimeric guanosine triphosphate-binding protein-coupled modulatory actions of motilin on K+ channels and postsynaptic γ-aminobutyric acid receptors in mouse medial vestibular nuclear neurons.

Eur. J. Neurosci. 37(3) , 339-50, (2013)

Some central nervous system neurons express receptors of gastrointestinal hormones, but their pharmacological actions are not well known. Previous anatomical and unit recording studies suggest that a group of cerebellar Purkinje cells express motilin receptor...

Gastrointestinal dysmotility: evidence and clinical management.

Curr. Opin. Clin. Nutr. Metab. Care 16(2) , 209-16, (2013)

Gastrointestinal dysmotility and dysfunction underlie our difficulties in providing adequate nutrition by the enteral route to our critically ill patients.Recent studies have quantified gastric emptying and nutrient absorption. Slow gastric emptying is common...

Effects of intrathecal opioids combined with low-dose naloxone on motilin and its receptor in a rat model of postoperative pain

Life Sci. 103(2) , 88-94, (2014)

Aims To investigate the effects of intrathecal morphine and fentanyl combined with low-dose naloxone on the expression of motilin and its receptor in a rat model of postoperative pain.

Ghrelin and motilin in the gastrointestinal system.

Curr. Pharm. Des. 18(31) , 4755-65, (2012)

Human ghrelin and human motilin, belonging to the ghrelin/motilin-related peptide family, share 36% amino acid sequence identity, while the human ghrelin receptor exhibits a remarkable 50% overall identity with the human motilin receptor. In addition to their...

Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptors.

Eur. J. Pharmacol. 699(1-3) , 48-54, (2013)

Paradoxically, erythromycin is associated with nausea when used as an antibiotic but at lower doses erythromycin activates motilin receptors and is used to treat delayed gastric emptying and nausea. The aim of this study was to characterise pro- and anti-emet...

Transcription factor binding site polymorphism in the motilin gene associated with left-sided displacement of the abomasum in German Holstein cattle.

PLoS ONE 7(4) , e35562, (2012)

Left-sided displacement of the abomasum (LDA) is a common disease in many dairy cattle breeds. A genome-wide screen for QTL for LDA in German Holstein (GH) cows indicated motilin (MLN) as a candidate gene on bovine chromosome 23. Genomic DNA sequence analysis...

Gastric emptying and symptoms of bulimia nervosa: effect of a prokinetic agent.

Physiol. Behav. 106(2) , 238-42, (2012)

Previous studies have suggested that delayed gastric emptying and abnormal postprandial release of hormones that influence satiation, particularly cholecystokinin (CCK), may play an important role in the pathophysiology of bulimia nervosa (BN). This study was...

The motilin gene evolved a new function in kangaroo rats and kangaroo mice (Dipodomyinae).

J. Mol. Evol. 75(3-4) , 112-8, (2012)

The motilin receptor gene was lost in the ancestral lineage of rodents. Subsequently, the gene encoding its ligand, motilin, has experienced different evolutionary fates. Previous genomic analyses had shown that the motilin gene (MLN) became a pseudogene inde...

Influence of acute exposure to high altitude on basal and postprandial plasma levels of gastroenteropancreatic peptides.

PLoS ONE 7(9) , e44445, (2012)

Acute mountain sickness (AMS) is characterized by headache often accompanied by gastrointestinal complaints that vary from anorexia through nausea to vomiting. The aim of this study was to investigate the influence of high altitude on plasma levels of gastroe...

The effect of continuous jejunal interposition on gastrointestinal hormones after distal gastrectomy.

Bosn. J. Basic Med. Sci. 12(1) , 10-4, (2012)

The objective of our study was to determine the effect of continuous jejunal interposition on gastrointestinal hormones after distal gastrectomy, and lay a foundation for surgical management.Distal subtotal gastrectomy experimental model were established on 2...