STF-62247
STF-62247 structure
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Common Name | STF-62247 | ||
|---|---|---|---|---|
| CAS Number | 315702-99-9 | Molecular Weight | 267.349 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 444.8±47.0 °C at 760 mmHg | |
| Molecular Formula | C15H13N3S | Melting Point | 174.66° C | |
| MSDS | Chinese USA | Flash Point | 222.8±29.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Novel small-molecule SIRT1 inhibitors induce cell death in adult T-cell leukaemia cells.
Sci. Rep. 5 , 11345, (2015) Adult T-cell leukaemia/lymphoma (ATL) is an aggressive T-cell malignancy that develops after long-term infection with human T-cell leukaemia virus (HTLV)-1. The identification of new molecular targets for ATL prevention and treatment is desired. SIRT1, a nico... |
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Targeted therapy for the loss of von Hippel-Lindau in renal cell carcinoma: a novel molecule that induces autophagic cell death.
Autophagy 4(7) , 944-6, (2008) Radiation and conventional cytotoxic chemotherapies are ineffective in treating renal cancer. Approximately 75 percent of renal cell carcinoma (RCC) is associated with an inactivation of the tumor suppressor gene von Hippel-Lindau (VHL). We exploited the poss... |
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A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Autophagy 8 , 677-89, (2012) Autophagy is a conserved constitutive cellular process, responsible for the degradation of dysfunctional proteins and organelles. Autophagy plays a role in many diseases such as neurodegeneration and cancer; however, to date, conventional autophagy detection ... |