Deoxyadenosine monophosphate
Deoxyadenosine monophosphate structure
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Common Name | Deoxyadenosine monophosphate | ||
|---|---|---|---|---|
| CAS Number | 653-63-4 | Molecular Weight | 331.222 | |
| Density | 2.2±0.1 g/cm3 | Boiling Point | 753.5±70.0 °C at 760 mmHg | |
| Molecular Formula | C10H14N5O6P | Melting Point | 148 °C | |
| MSDS | Chinese USA | Flash Point | 409.5±35.7 °C | |
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Development of an electrochemical surface-enhanced Raman spectroscopy (EC-SERS) aptasensor for direct detection of DNA hybridization.
Phys. Chem. Chem. Phys. 17 , 21356-63, (2015) Rapid detection of disease biomarkers at the patient point-of-care is essential to timely and effective treatment. The research described herein focuses on the development of an electrochemical surface-enhanced Raman spectroscopy (EC-SERS) DNA aptasensor capa... |
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Evaluation of column hardware on liquid chromatography-mass spectrometry of phosphorylated compounds.
J. Chromatogr. A. 1381 , 125-31, (2015) The influences of column hardware, such as chromatographic tubes and frits, on liquid chromatography-mass spectrometry (LC-MS) analysis of phosphorylated compounds were evaluated. The signal to noise ratio (S/N) and the intensity of flavin adenine dinucleotid... |
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Organocatalytic removal of formaldehyde adducts from RNA and DNA bases.
Nature Chemistry 7 , 752-8, (2015) Formaldehyde is universally used to fix tissue specimens, where it forms hemiaminal and aminal adducts with biomolecules, hindering the ability to retrieve molecular information. Common methods for removing these adducts involve extended heating, which can ca... |
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Robust Antibody-Antigen Complexes Prediction Generated by Combining Sequence Analyses, Mutagenesis, In Vitro Evolution, X-ray Crystallography and In Silico Docking.
J. Mol. Biol. 427 , 2647-62, (2015) Hu 15C1 is a potent anti-human Toll-like receptor 4 (TLR4) neutralizing antibody. To better understand the molecular basis of its biological activity, we used a multidisciplinary approach to generate an accurate model of the Hu 15C1-TLR4 complex. By combining... |
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Metal free columns for determination of deoxynucleotide monophosphate by liquid chromatography/mass spectrometry and application to oligonucleotide.
J. Chromatogr. A. 1406 , 210-4, (2015) We have developed a highly sensitive method for the analysis of deoxynucleotide monophosphates (dNMPs), which involves the use of liquid chromatography/mass spectrometry (LC/MS) and a new metal-free column. The new column solves the problem that the phosphate... |
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Structure-based functional identification of Helicobacter pylori HP0268 as a nuclease with both DNA nicking and RNase activities.
Nucleic Acids Res. 43 , 5194-207, (2015) HP0268 is a conserved, uncharacterized protein from Helicobacter pylori. Here, we determined the solution structure of HP0268 using three-dimensional nuclear magnetic resonance (NMR) spectroscopy, revealing that this protein is structurally most similar to a ... |
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Two novel dATP analogs for DNA photoaffinity labeling.
Nucleic Acids Res. 28 , 4382-4390, (2000) Two new photoreactive dATP analogs, N(6)-[4-azidobenzoyl-(2-aminoethyl)]-2'-deoxyadenosine-5'-triphospha+ ++ te (AB-dATP) and N(6)-[4-[3-(trifluoromethyl)-diazirin-3-yl]benzoyl-(2-aminoethyl) ]-2 '-deoxyadenosine-5'-triphosphate (DB-dATP), were synthesized fr... |
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The effects of addition of mononucleotides on Sma nuc endonuclease activity.
ScientificWorldJournal 2012 , 454176, (2012) Examination of the effects of mononucleotides on Sma nuc endonuclease originated from Gram negative bacterium Serratia marcescens displayed that any mononucleotide produced by Sma nuc during hydrolysis of DNA or RNA may regulate the enzyme activity affecting ... |
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Formation of dAMP-glycerol and dAMP-Tris derivatives by Thermococcus kodakaraensis DNA primase.
J. Biol. Chem. 287(20) , 16220-9, (2012) In the presence of dATP, glycerol, and Tris buffer, the DNA primase isolated from Thermococcus kodakaraensis catalyzed the formation of dAMP and two products that were identified as dAMP-glycerol and dAMP-Tris. These products were formed by the T. kodakaraens... |
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Density functional theory studies on the oxidation of 5'-dGMP and 5'-dAMP by a platinum(IV) complex.
Inorg. Chem. 51(15) , 8002-13, (2012) Density functional theory has been used to investigate the oxidation of a guanine nucleotide by platinum(IV), a process that can be important in the degradation of DNA. For the first time, we have provided a comprehensive mechanism for all of the steps in thi... |