Cercosporin

Cercosporin Structure
Cercosporin structure
Common Name Cercosporin
CAS Number 35082-49-6 Molecular Weight 534.51100
Density 1.59g/cm3 Boiling Point 886.9ºC at 760mmHg
Molecular Formula C29H26O10 Melting Point N/A
MSDS Chinese USA Flash Point 299ºC

CbCTB2, an O-methyltransferase is essential for biosynthesis of the phytotoxin cercosporin and infection of sugar beet by Cercospora beticola.

BMC Plant Biol. 13 , 50, (2013)

Cercospora leaf spot disease, caused by the fungus Cercospora beticola, is the most destructive foliar disease of sugar beets (Beta vulgaris) worldwide. Cercosporin, a light-inducible toxin, is essential for necrosis of the leaf tissue and development of the ...

Antiproliferative activity of epi-cercosporin in human solid tumor cell lines.

Nat. Prod. Commun. 8(2) , 187-9, (2013)

From cultures of Cercospora piaropi, a phytopathogenic fungus isolated from symptomatic leaves of water hyacinth was obtained a red compound, which, according to the spectroscopic data, was epi-cercosporin. It showed in vitro antiproliferative activity agains...

Reactive oxygen species in plant pathogenesis: the role of perylenequinone photosensitizers.

Antioxid. Redox Signal. 19(9) , 970-89, (2013)

Reactive oxygen species (ROS) play multiple roles in interactions between plants and microbes, both as host defense mechanisms and as mediators of pathogenic and symbiotic associations. One source of ROS in these interactions are photoactivated, ROS-generatin...

The Cercospora nicotianae gene encoding dual O-methyltransferase and FAD-dependent monooxygenase domains mediates cercosporin toxin biosynthesis.

Fungal Genet. Biol. 44(5) , 444-54, (2007)

Cercosporin, a photo-activated, non-host-selective phytotoxin produced by many species of the plant pathogenic fungus Cercospora, causes peroxidation of plant cell membranes by generating reactive oxygen species and is an important virulence determinant. Here...

Analysis of the cercosporin polyketide synthase CTB1 reveals a new fungal thioesterase function.

Chem. Commun. (Camb.) 48(96) , 11772-4, (2012)

The polyketide synthase CTB1 is demonstrated to catalyze pyrone formation thereby expanding the known biosynthetic repertoire of thioesterase domains in iterative, non-reducing polyketide synthases.

Expression of the yeast cpd1 gene in tobacco confers resistance to the fungal toxin cercosporin.

Biomol. Eng. 24(2) , 245-51, (2007)

Many phytopathogenic species of the fungus Cercospora produce cercosporin, a photoactivated perylenequinone toxin that belongs to a family of photosensitizers, which absorb light energy and produce extremely cytotoxic, reactive oxygen species. The cpd1 (cerco...

Superoxide dismutase transgenes in sugarbeets confer resistance to oxidative agents and the fungus C. beticola.

Transgenic Res. 13(3) , 225-33, (2004)

Sugarbeets carrying superoxide dismutase transgenes were developed in order to investigate the possibility of enhancing their resistance to oxidative stress. Binary T-DNA vectors carrying the chloroplastic and cytosolic superoxide dismutase genes from tomato,...

Functional characterization of three genes encoding putative oxidoreductases required for cercosporin toxin biosynthesis in the fungus Cercospora nicotianae.

Microbiology 153(Pt 8) , 2781-90, (2007)

Cercosporin is a non-host-selective, photoactivated polyketide toxin produced by many phytopathogenic Cercospora species, which plays a crucial role during pathogenesis on host plants. Upon illumination, cercosporin converts oxygen molecules to toxic superoxi...

Identification of genes differentially expressed in the phytopathogenic fungus Cercospora nicotianae between cercosporin toxin-resistant and -susceptible strains.

FEMS Microbiol. Lett. 275(2) , 326-37, (2007)

Plant pathogens from the genus Cercospora produce cercosporin, a photoactivated fungal toxin that generates toxic reactive oxygen species. Mechanisms governing toxin auto-resistance in Cercospora spp. are poorly understood. In this work, suppressive subtracti...

Production of cercosporin toxin by the phytopathogenic Cercospora fungi is affected by diverse environmental signals.

Can. J. Microbiol. 54(4) , 259-69, (2008)

Cercosporin is a polyketide phytotoxin produced by many phytopathogenic Cercospora spp. We investigated environmental signals that have elaborate control of cercosporin production. Light is the most critical factor for cercosporin production. Cercospora nicot...