δ-Hexachlorocyclohexane
δ-Hexachlorocyclohexane structure
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Common Name | δ-Hexachlorocyclohexane | ||
|---|---|---|---|---|
| CAS Number | 319-86-8 | Molecular Weight | 290.830 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 288.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C6H6Cl6 | Melting Point | 113-115ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 157.5±23.9 °C | |
| Symbol |
GHS06, GHS08, GHS09 |
Signal Word | Danger | |
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Heptachlor epoxide induces a non-capacitative type of Ca2+ entry and immediate early gene expression in mouse hepatoma cells.
Toxicology 220(2-3) , 218-31, (2006) The effects of the organochlorine (OC) liver tumor promoter heptachlor epoxide (HE) and a related non-tumor promoting OC, delta-hexachlorocyclohexane (delta-HCH), on the dynamics of intracellular calcium (Ca2+) were investigated in mouse 1c1c7 hepatoma cells.... |
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Pesticide residues in fruits at the market level in Accra Metropolis, Ghana, a preliminary study.
Environ. Monit. Assess. 175(1-4) , 551-61, (2011) A number of pesticide residues in fruits were monitored at five markets in the Accra Metropolis for almost a year. Locally produced fruits (pawpaw and tomato) and imported apple were purchased from these selected markets in the metropolis and analyzed for pes... |
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Monitoring of organochlorine pesticides in and around Keoladeo National Park, Bharatpur, Rajasthan, India.
Environ. Monit. Assess. 184(9) , 5295-300, (2012) Keoladeo National Park (KNP) is an important wintering ground for thousands of birds that undertake a perilous journey over the Himalaya to make a seasonal home in a wetland ecosystem. However, this wetland is now getting polluted by various types of contamin... |
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Enantioselective dehydrochlorination of δ-Hexachlorocyclohexane and δ-Pentachlorocyclohexene by LinA1 and LinA2 from Sphingobium indicum B90A.
Appl. Environ. Microbiol. 79(19) , 6180-3, (2013) δ-Hexachlorocyclohexane (δ-HCH), one of the prevalent isomers of technical HCH, was enantioselectively dehydrochlorinated by the dehydrochlorinases LinA1 and LinA2 from Sphingobium indicum B90A to the very same δ-pentachlorocyclohexene enantiomer. Racemic δ-p... |
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Mechanisms of delta-hexachlorocyclohexane toxicity: I. Relationship between altered ventricular myocyte contractility and ryanodine receptor function.
J. Pharmacol. Exp. Ther. 289(1) , 477-85, (1999) Several isomers of hexachlorocyclohexanes (HCHs) have been shown to be toxic to mammals. Previous studies have revealed that the delta isomer (delta-HCH) was particularly potent toward disrupting Ca2+ homeostasis in a variety of excitable and nonexcitable cel... |
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Analysis of the role of LinA and LinB in biodegradation of delta-hexachlorocyclohexane.
Environ. Microbiol. 9(9) , 2331-40, (2007) Commercial formulations of hexachlorocyclohexane (HCH) consist of a mixture of four isomers, alpha, beta, gamma and delta. All these four isomers are toxic and recalcitrant pollutants. Sphingobium (formerly Sphingomonas) sp. strain BHC-A is able to degrade al... |
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Determination and assessment of HCHs and DDTs residues in sediments from Lake Dongting, China.
Environ. Monit. Assess. 116(1-3) , 157-67, (2006) The contamination of organochlorine pesticides hexachlorocyclohexane (HCH) and Dichlorodiphenyltrichloroethane (DDT) and their eco-environmental assessment in surface sediments from Lake Dongting, the second-largest freshwater lake in China, were studied. Con... |
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Effects of gamma-HCH and delta-HCH on human recombinant GABA(A) receptors: dependence on GABA(A) receptor subunit combination.
Br. J. Pharmacol. 132(1) , 205-12, (2001) 1. Human GABA(A) receptors containing different alpha and beta subunits with or without the gamma 2S or gamma 2L subunits were expressed in Xenopus oocytes and the effects of the insecticides gamma- and delta-hexachlorocyclohexane (gamma-HCH and delta-HCH, re... |
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Properties of ryanodine receptors in cultured cerebellar granule neurons: effects of hexachlorocyclohexane isomers and calcium.
J. Neurosci. Res. 47(1) , 27-33, (1997) The binding of [3H]ryanodine was determined in microsomal membrane preparations obtained from cultured cerebellar granule cells. A KD of 1 nM and a Bmax of 64 fmol/mg protein were calculated from saturation experiments. This binding was calcium dependent and ... |
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Effects of electron donors on the microbial reductive dechlorination of hexachlorocyclohexane and on the environment.
J. Biosci. Bioeng. 113(6) , 765-70, (2012) The reductive biotransformation of α-, β-, γ-, and δ-hexachlorocyclohexane isomers was investigated using five alternative electron donors (i.e., glucose plus methanol, glucose only, methanol only, acetate, and ethanol) in a batch assay of an HCH-dechlorinati... |