2-AMINO-5-NITROPENOL

2-AMINO-5-NITROPENOL Structure
2-AMINO-5-NITROPENOL structure
Common Name 2-AMINO-5-NITROPENOL
CAS Number 121-88-0 Molecular Weight 154.123
Density 1.5±0.1 g/cm3 Boiling Point 364.0±32.0 °C at 760 mmHg
Molecular Formula C6H6N2O3 Melting Point 198-202 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 173.9±25.1 °C
Symbol GHS07
GHS07
Signal Word Warning

Effect of gradient steepness on the kinetic performance limits and peak compression for reversed-phase gradient separations of small molecules.

J. Chromatogr. A. 1409 , 152-8, (2015)

The effect of gradient steepness on the kinetic performance limits and peak compression effects has been assessed in gradient mode for the separation of phenol derivatives using columns packed with 2.6μm core-shell particles. The effect of mobile-phase veloci...

Final report on the safety assessment of amino nitrophenols as used in hair dyes.

Int. J. Toxicol. 28(6 Suppl 2) , 217S-51S, (2009)

2-Amino-3-nitrophenol, 2-amino-4-nitrophenol, 2-amino-5-nitrophenol, 4-amino-3-nitrophenol, 4-amino-2-nitrophenol, 2-amino-4-nitrophenol sulfate, 3-nitro-p-hydroxyethylaminophenol, and 4-hydroxypropylamino-3-nitrophenol are substituted aromatic compounds used...

[Simultaneous determination of 11 aminophenols in hair dyes by high performance liquid chromatography].

Se Pu 30(9) , 870-5, (2012)

An analytical method was developed for the simultaneous determination of 11 aminophenols in direct and oxidized hair dyes by high performance liquid chromatography (HPLC). The samples were extracted with methanol using sodium bisulfite for anti-oxidation. The...

Synthesis of novel 7-benzylamino-2H-1,4-benzoxazin-3(4H)-ones as anticonvulsant agents.

Eur. J. Med. Chem. 43 , 1216-21, (2008)

A series of 7-benzylamino-2H-1,4-benzoxazin-3(4H)-ones were synthesized using 2-amino-5-nitrophenol as a starting material. Their anticonvulsant activities were evaluated by the maximal electroshock test (MES test) and their neurotoxicity was evaluated by the...

anticonvulsant and toxicity evaluation of newer 4H-benzo[1,4]oxazin-3-ones: The effect of two hydrogen bonding domains.

Arch. Pharm. (Weinheim) 343(11-12) , 657-63, (2010)

A series of (Z)-2-(substituted aryl)-N-(3-oxo-4-(substituted carbamothioyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl) hydrazine carboxamides (6a-r) was synthesized using 2-amino-5-nitrophenol as a starting material. All the synthesized compounds possessed two ...

2-Amino-5-nitrophenol.

IARC Monogr. Eval. Carcinog. Risks Hum. 57 , 177-84, (1993)

Metal-mediated oxidative DNA damage induced by nitro-2-aminophenols.

Cancer Lett. 126(1) , 67-74, (1998)

Two hair dye components, carcinogenic 4-nitro-2-aminophenol and 5-nitro-2-aminophenol, induced Cu(II)-dependent DNA cleavage frequently at thymine and guanine residues in DNA fragments obtained from the c-Ha-ras-1 protooncogene. When the p53 tumor suppressor ...