4-Oxo-4H-chromene-3-carbaldehyde
4-Oxo-4H-chromene-3-carbaldehyde structure
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Common Name | 4-Oxo-4H-chromene-3-carbaldehyde | ||
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| CAS Number | 17422-74-1 | Molecular Weight | 174.153 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 303.1±42.0 °C at 760 mmHg | |
| Molecular Formula | C10H6O3 | Melting Point | 151-153 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 134.7±27.9 °C | |
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Formylchromone exhibits salubrious effects against nitrosodiethylamine mediated early hepatocellular carcinogenesis in rats.
Chem. Biol. Interact. 219 , 175-83, (2014) The salubrious effects of 3-Formylchromone (3-FC) against nitrosodiethylamine (NDEA) mediated early hepatocellular carcinogenesis was investigated in vivo by this study. Male Wistar rats were administered three interspersed intraperitoneal injections of NDEA ... |
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3-Formylchromones: potential antiinflammatory agents.
Eur. J. Med. Chem. 45 , 4058-64, (2010) The synthesis and characterization of 3-formylchromone (1) and its derivatives 2-24 and evaluation of their potential antiinflammatory activities is reported here. These compounds were characterized by (1)H NMR, EI MS, IR, and UV spectroscopic techniques and ... |
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Synthesis of quinolines from 3-formylchromone.
J. Org. Chem. 73(15) , 6010-3, (2008) A facile and versatile procedure for the synthesis of 3-(2-hydroxybenzoyl)quinolines and 7H-chromeno[3,2-c]quinolin-7-ones was elaborated on the basis of TMSCl-mediated recyclization of 3-formylchromone with various anilines. Limitations and scope of this met... |
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Loss of H2 and CO from protonated aldehydes in electrospray ionization mass spectrometry.
Rapid Commun. Mass Spectrom. 28(17) , 1871-82, (2014) Electrospray ionization mass spectrometry (ESI-MS) of many protonated aldehydes shows loss of CO as a major fragmentation pathway. However, we find that certain aldehydes undergo loss of H2 followed by reaction with water in the collision cell. This complicat... |
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Thermal solvent-free synthesis of chromonyl chalcones, pyrazolines and their in vitro antibacterial, antifungal activities.
J. Enzyme Inhib. Med. Chem. 27(1) , 84-91, (2012) A facile and ecofriendly synthesis of new chromonyl chalcones 3a-b from 3-formylchromone 1 and active methyl compounds 2a-b is reported under thermal solvent-free heating condition in good yields. The chromonyl chalcones 3a-b were used as intermediates under ... |
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A catalyst-free multicomponent domino sequence for the diastereoselective synthesis of (E)-3-[2-arylcarbonyl-3-(arylamino)allyl]chromen-4-ones.
Beilstein J. Org. Chem. 10 , 459-65, (2014) The three-component domino reactions of (E)-3-(dimethylamino)-1-arylprop-2-en-1-ones, 3-formylchromone and anilines under catalyst-free conditions afforded a library of novel (E)-3-(2-arylcarbonyl-3-(arylamino)allyl)-4H-chromen-4-ones in good to excellent yie... |