Ethyl 4-hydroxyquinoline-2-carboxylate

Ethyl 4-hydroxyquinoline-2-carboxylate Structure
Ethyl 4-hydroxyquinoline-2-carboxylate structure
Common Name Ethyl 4-hydroxyquinoline-2-carboxylate
CAS Number 24782-43-2 Molecular Weight 217.221
Density 1.2±0.1 g/cm3 Boiling Point 343.7±42.0 °C at 760 mmHg
Molecular Formula C12H11NO3 Melting Point 216-218ºC(lit.)
MSDS Chinese USA Flash Point 161.7±27.9 °C
Symbol GHS07
GHS07
Signal Word Warning

Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2.

Br. J. Pharmacol. 162 , 733-748, (2011)

GPR35 is a poorly characterized G protein-coupled receptor at which kynurenic acid has been suggested to be the endogenous ligand. We wished to test this and develop assays appropriate for the study of this receptor.Human and rat orthologues of GPR35 were eng...