METHYLMAGNESIUM BROMIDE

METHYLMAGNESIUM BROMIDE Structure
METHYLMAGNESIUM BROMIDE structure
Common Name METHYLMAGNESIUM BROMIDE
CAS Number 75-16-1 Molecular Weight 119.24400
Density 1.035 g/mL at 25 °C Boiling Point 78-80ºC
Molecular Formula CH3BrMg Melting Point 0ºC
MSDS Chinese Flash Point 77 °F
Symbol GHS02 GHS05 GHS07
GHS02, GHS05, GHS07
Signal Word Danger

Discovery of dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in neurodegeneration models.

J. Med. Chem. 58(1) , 401-18, (2015)

Dual leucine zipper kinase (DLK, MAP3K12) was recently identified as an essential regulator of neuronal degeneration in multiple contexts. Here we describe the generation of potent and selective DLK inhibitors starting from a high-throughput screening hit. Us...