Fumaric Acid Monoethyl Ester Magnesium Salt
Fumaric Acid Monoethyl Ester Magnesium Salt structure
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Common Name | Fumaric Acid Monoethyl Ester Magnesium Salt | ||
|---|---|---|---|---|
| CAS Number | 83918-60-9 | Molecular Weight | 310.54000 | |
| Density | N/A | Boiling Point | 261.6ºC at 760 mmHg | |
| Molecular Formula | C12H14MgO8 | Melting Point | 169ºC (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 109.6ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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The antipsoriatic dimethyl-fumarate suppresses interferon-gamma -induced ICAM-1 and HLA-DR expression on hyperproliferative keratinocytes. Quantification by a culture plate-directed APAAP-ELISA technique.
Eur. J. Dermatol. 8(1) , 29-32, (1998) The derivatives of fumaric acid show antipsoriatic effects but details of the mechanism of action are largely unknown. The study focused on the effect of fumaric acid, dimethyl-fumarate, Zn-, Ca- and Mg-monoethyl-fumarate on the interferon-gamma (IFN-gamma)-i... |
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Inhibition of dendritic cell differentiation by fumaric acid esters.
J. Invest. Dermatol. 116(2) , 203-8, (2001) Fumaric acid esters have proved to be effective for the systemic treatment of severe psoriasis vulgaris. These compounds have been shown to induce a Th2-like cytokine secretion pattern in T cells and to reduce keratinocyte proliferation in vitro. Dendritic ce... |
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