2,7-Diaminofluorene
2,7-Diaminofluorene structure
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Common Name | 2,7-Diaminofluorene | ||
|---|---|---|---|---|
| CAS Number | 525-64-4 | Molecular Weight | 196.248 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 467.0±38.0 °C at 760 mmHg | |
| Molecular Formula | C13H12N2 | Melting Point | 160-162 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 283.6±26.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Genotoxic potency in Drosophila melanogaster of selected aromatic amines and polycyclic aromatic hydrocarbons as assayed in the DNA repair test.
Mutat. Res. 290(2) , 175-82, (1993) Drosophila melanogaster stock consisting of meiotic recombination deficient (Rec-) double mutant mei-9a mei-41D5 males and Rec+ females was exposed at the larval stage to an aromatic amine or a polycyclic aromatic hydrocarbon. After emergence as adult flies, ... |
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[An interesting peroxidase staining.--utilization of blended substrate of mixed 2, 7-FDA and Laurent's acid-- (author's transl)].
Rinsho Byori. 29(6) , 613-6, (1981)
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Sensitive assay systems for detection of hemoglobin with 2,7-diaminofluorene: histochemistry and colorimetry for erythrodifferentiation.
Anal. Biochem. 149 , 117, (1985) Sensitive and rapid assays, colorimetry and histochemistry, for hemoglobin in erythroid cells are established. The assays are based on pseudoperoxidase activity of hemoglobin using 2,7-diaminofluorene as a hydrogen donor for the peroxidase, instead of benzidi... |
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[Study on the antimutagenicity of curcumin].
Wei Sheng Yan Jiu 27(4) , 263-5, (1998) Curcumin is a coloring additive used in food, which has many biological functions. In order to provide basic information on its anticarcinogenicity, the antimutagenicity of curcumin was determined by Ames test and micronuclei test. The results indicated that ... |
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Quantitation of erythroid differentiation in vitro using a sensitive colorimetric assay for hemoglobin.
Exp. Hematol. 15(1) , 85-92, (1987) We have developed a new colorimetric method to detect early erythroid clonogenic progenitor cells by virtue of their hemoglobin-containing progeny in vitro. The method relies upon the specific oxidation of 2,7-diaminofluorene (DAF) by the pseudoperoxidase act... |
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Endothelial cells suppress granulocyte clusters and stimulate large granulocyte colonies in culture.
Clin. Invest. Med. 8(2) , 160-6, (1985) Endothelial cells have been shown to produce granulopoietic colony stimulating activity (CSA) under the regulatory control of a humoral factor, MRA produced by blood monocytes. An endothelial cell-derived granulopoietic inhibitory factor has also been describ... |
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Procarcinogen activation by rat and human mammary extracts.
Carcinogenesis 7(6) , 899-905, (1986) Sprague-Dawley rat mammary gland is extremely sensitive to tumorigenesis by single or multiple doses of several polycyclic aromatic hydrocarbons. We obtained quantitative data on the in vitro mutagenic activation of several procarcinogens by 9000 g supernatan... |
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A modified colorimetric method for the measurement of phagocytosis and antibody-dependent cell cytotoxicity using 2,7-diaminofluorene.
J. Immunol. Methods 151(1-2) , 255-60, (1992) A sensitive and rapid colorimetric method for the in vitro determination of phagocytic activity and antibody-dependent cell-mediated cytotoxicity (ADCC) is described. The assay uses red blood cells (RBC) as target cells and relies on the specific oxidation of... |
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Diaminofluorene is more sensitive than benzidine for detecting hemoglobin in erythropoietin responsive J2E cells.
Hemoglobin 19(1-2) , 7-19, (1995) We have used the diaminofluorene stain to detect hemoglobin production in J2E cells following erythropoietin-induced differentiation. The pseudo-peroxidase activity of hemoglobin produces a colored product, fluorene blue, which can be measured spectrophotomet... |
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Use of the DAF assay to assess the functional properties of polyclonal and monoclonal RhD antibodies.
Vox Sang. 71(1) , 30-6, (1996) The mechanism whereby passive Rh (D) immunoglobulins suppress the fetomaternal alloimmunization is still unclear. New in vitro tests are needed to better characterize the functional properties of polyclonal anti-Ds. The DAF assay was developed to monitor the ... |