Fmoc-D-Tic-OH

Fmoc-D-Tic-OH Structure
Fmoc-D-Tic-OH structure
Common Name Fmoc-D-Tic-OH
CAS Number 130309-33-0 Molecular Weight 399.439
Density 1.3±0.1 g/cm3 Boiling Point 629.9±55.0 °C at 760 mmHg
Molecular Formula C25H21NO4 Melting Point 160-164 °C
MSDS Chinese USA Flash Point 334.7±31.5 °C

Bradykinin receptor antagonists containing N-substituted amino acids: in vitro and in vivo B(2) and B(1) receptor antagonist activity.

J. Med. Chem. 39 , 1472, (1996)

We report a systematic probing of the structural requirements of the bradykinin (BK) type 2 (B(2)) receptor for antagonist activity by incorporating N-alkyl-amino acid residues at positions 7 and 8 of a potent antagonist sequence. Compound 1 (D-Arg(0)-Arg(1)-...

Design and synthesis of new linear and cyclic bradykinin antagonists.

J. Med. Chem. 39 , 2095, (1996)

We report here on the synthesis and pharmacological properties of a new series of small linear and cyclic peptides derived from the five C-terminal amino acid residues of second-generation bradykinin receptor antagonists. Variations of the two first residues ...