![]() Fmoc-D-Tic-OH structure
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Common Name | Fmoc-D-Tic-OH | ||
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CAS Number | 130309-33-0 | Molecular Weight | 399.439 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 629.9±55.0 °C at 760 mmHg | |
Molecular Formula | C25H21NO4 | Melting Point | 160-164 °C | |
MSDS | Chinese USA | Flash Point | 334.7±31.5 °C |
Bradykinin receptor antagonists containing N-substituted amino acids: in vitro and in vivo B(2) and B(1) receptor antagonist activity.
J. Med. Chem. 39 , 1472, (1996) We report a systematic probing of the structural requirements of the bradykinin (BK) type 2 (B(2)) receptor for antagonist activity by incorporating N-alkyl-amino acid residues at positions 7 and 8 of a potent antagonist sequence. Compound 1 (D-Arg(0)-Arg(1)-... |
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Design and synthesis of new linear and cyclic bradykinin antagonists.
J. Med. Chem. 39 , 2095, (1996) We report here on the synthesis and pharmacological properties of a new series of small linear and cyclic peptides derived from the five C-terminal amino acid residues of second-generation bradykinin receptor antagonists. Variations of the two first residues ... |
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