trans-2-phenylcyclopropyl isocyanate

trans-2-phenylcyclopropyl isocyanate Structure
trans-2-phenylcyclopropyl isocyanate structure
Common Name trans-2-phenylcyclopropyl isocyanate
CAS Number 63009-74-5 Molecular Weight 159.18500
Density 1.074 g/mL at 25ºC(lit.) Boiling Point 75-76ºC0.5 mm Hg(lit.)
Molecular Formula C10H9NO Melting Point N/A
MSDS Chinese USA Flash Point 225 °F
Symbol GHS07
GHS07
Signal Word Warning

Identification of a series of PPAR gamma/delta dual agonists via solid-phase parallel synthesis.

Bioorg. Med. Chem. Lett. 11(22) , 2959-62, (2001)

We have developed a general solid-phase synthesis for identification of PPAR ligands. Synthesis of a 480-member library led to the identification of a potent PPAR gamma/delta dual agonist 23. Compound 23 showed good plasma exposure in rats and demonstrated an...