phallacidin
phallacidin structure
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Common Name | phallacidin | ||
|---|---|---|---|---|
| CAS Number | 26645-35-2 | Molecular Weight | 846.90400 | |
| Density | 1.54 g/cm3 | Boiling Point | 1435.2ºC | |
| Molecular Formula | C37H50N8O13S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 821.8ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Intestinal epithelial cytoskeleton selectively constrains lumen-to-tissue migration of neutrophils.
Am. J. Physiol. 271(1 Pt 1) , C312-20, (1996) Migration of neutrophils (polymorphonuclear leukocytes; PMN) across polarized epithelia is asymmetrical: basolateral-to-apical (physiologically directed) migration is far more efficient than migration in the reverse direction, suggesting the presence of lumin... |
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A concept study on identification and attribution profiling of chemical threat agents using liquid chromatography-mass spectrometry applied to Amanita toxins in food.
Forensic Sci. Int. 221(1-3) , 44-9, (2012) Accidental or deliberate poisoning of food is of great national and international concern. Detecting and identifying potentially toxic agents in food is challenging due to their large chemical diversity and the complexity range of food matrices. A methodology... |
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Direct binding of F actin to the cytoplasmic domain of the alpha 2 integrin chain in vitro.
Biochem. Biophys. Res. Commun. 217(2) , 466-74, (1995) The transmembrane integrins have been shown to interact with the cytoskeleton via noncovalent binding between cytoplasmic domains (CDs) of integrin beta chains and various actin binding proteins within the focal adhesion complex. Direct or indirect integrin a... |
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Differential effects of actin cytoskeleton dynamics on equine infectious anemia virus particle production.
J. Virol. 78(2) , 882-91, (2004) Retrovirus assembly and budding involve a highly dynamic and concerted interaction of viral and cellular proteins. Previous studies have shown that retroviral Gag proteins interact with actin filaments, but the significance of these interactions remains to be... |
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Cucurbitacin I inhibits cell motility by indirectly interfering with actin dynamics.
PLoS ONE 5(11) , e14039, (2010) Cucurbitacins are plant natural products that inhibit activation of the Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) pathway by an unknown mechanism. They are also known to cause changes in the organization of the actin cyt... |
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Phallacidin stains the mitotic spindle of the diatom Pinnularia spp.
Cell Biol. Int. 28(8-9) , 565-9, (2004) Mitotic spindles of the diatom Pinnularia viritiformis stained with the fluorescent actin-labelling reagent bodipyphallacidin revealed actin among the chromosomes and extending along the spindle to the poles. This is the first report of actin's presence withi... |
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Tuning a polar molecule for selective cytoplasmic delivery by a pH (Low) insertion peptide.
Biochemistry 50(47) , 10215-22, (2011) Drug molecules are typically hydrophobic and small in order to traverse membranes to reach cytoplasmic targets, but we have discovered that more polar molecules can be delivered across membranes using water-soluble, moderately hydrophobic membrane peptides of... |
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Thrombin-induced alterations in endothelial cell cytoarchitectural and functional properties.
Semin. Thromb. Hemost. 20(4) , 417-25, (1994) alpha-Thrombin interacts with confluent bovine pulmonary artery endothelial cells to produce two types of actin microfilament rearrangements: (1) The loss of cortical actin correlates with interruption of barrier integrity, evident from increased permeability... |
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Direct measurement of neutrophil F-actin content in microvolume whole blood samples.
Int. Arch. Allergy Immunol. 110(4) , 325-31, (1996) The traditional methods of measuring F-actin content in neutrophils required a large blood sample and a series of isolation procedures. To reduce the disturbing effect on neutrophils, a new method was designed to measure the neutrophil F-actin content directl... |
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Growth inhibition and changes in morphology and actin distribution in Acetabularia acetabulum by phalloidin and phalloidin derivatives.
Protoplasma 220(3-4) , 209-18, (2003) Effects on morphology and microfilament structure caused by phalloidin, phallacidin, and some semisynthetic phalloidin derivatives were studied in vegetative cells of the green alga Acetabularia acetabulum (L.) Silva. All phalloidin derivatives (except for ph... |