Nicotinyl alcohol
Nicotinyl alcohol structure
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Common Name | Nicotinyl alcohol | ||
|---|---|---|---|---|
| CAS Number | 100-55-0 | Molecular Weight | 109.126 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 266.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C6H7NO | Melting Point | -7 °C | |
| MSDS | Chinese USA | Flash Point | 97.5±20.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Inhibitory effects of niacin and its analogues on induction of ornithine decarboxylase activity by diethylnitrosamine in rat liver.
Biochem. Pharmacol. 36(18) , 3015-9, (1987) Pharmacological doses of niacin and its analogues were given intraperitoneally to rats with and without coadministration of a hepatocarcinogenic dose of diethylnitrosamine (DEN), and their effects on the induction of ornithine decarboxylase (ODC, EC 4.1.1.17)... |
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The role of p53 in the cellular toxicity by active trans-platinum complexes containing isopropylamine and hydroxymethylpyridine.
Eur. J. Med. Chem. 45(1) , 134-41, (2010) Despite some initial research that reported a lack of activity of trans geometry, complexes with general formula trans-[PtCl2(L)(L')] exhibit an important cytotoxic activity in cisplatin-sensitive and resistant cell lines. Based on the proposed mechanism of a... |
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Oxidation of alcohols using a manganese (II) complex based on a pentakis benzimidazole amide ligand.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 74(2) , 536-43, (2009) A pentakis benzimidazole based penta-amide ligand diethylenetriamine-N,N,N',N',N''-pentakis(2-methyl benzimidazolyl)penta-amide [GBDTPA] has been synthesized and utilized to prepare Mn (II) complexes of general composition [Mn(2)(GBDTPA)X(4)], where X is an e... |
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Enzymatic oxidation of NADP+ to its 4-oxo derivative is a side-reaction displayed only by the adrenodoxin reductase type of ferredoxin-NADP+ reductases.
FEBS J. 274(15) , 3998-4007, (2007) We have previously shown that Mycobacterium tuberculosis FprA, an NADPH-ferredoxin reductase homologous to mammalian adrenodoxin reductase, promotes the oxidation of NADP(+) to its 4-oxo derivative 3-carboxamide-4-pyridone adenine dinucleotide phosphate [Boss... |
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Unusual but reversible hepatic lesions following long-term treatment with pyridylcarbinol for familial hypercholesterolemia.
Klin. Wochenschr. 66(14) , 647-50, (1988) We report two cases of unusual hepatic lesions following years of monotherapy with pyridylcarbinol (timespan) in a daily dose of 1.35 to 1.5 g for familial hypercholesterolemia. Mild elevations of liver enzymes correlated to a large tumor-like mass in the gal... |
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Purification and kinetic characterization of Haemophilus parasuis malate dehydrogenase.
Arch. Biochem. Biophys. 344(1) , 176-83, (1997) Haemophilus parasuis malate dehydrogenase ((S)-malate:NAD+ oxidoreductase; EC 1.1.1.37) isolated from cell sonicates was purified 584-fold to electrophoretic homogeneity with a 19% recovery and a specific activity of 222 units/mg protein. SDS-polyacrylamide g... |
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The strip test for hypolactasia also works without ethanol.
Scand. J. Gastroenterol. 23(7) , 851-5, (1988) Detection of urinary galactose with a special test strip has been shown to work well with the lactose tolerance test with ethanol. In this study the strips were used in combination with a lactose load alone or with another alcohol, beta-pyridylcarbinol, and t... |
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Influence of powder characteristics of bulk substance with pharmaceutical processing.
Drug Dev. Ind. Pharm. 24(9) , 857-61, (1998) The physicochemical properties of crystals can vary with the crystallization procedure employed in their isolation and purification. Moreover, the success of any direct-tableting procedure is directly effected by the quality of the crystals used in this proce... |
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Effect of beta-pyridyl-carbinol on platelet aggregation.
Thromb. Res. 49(6) , 501-8, (1988) We studied the anti-platelet aggregation activity of beta-pyridyl-carbinol (b-PC) (Ronicol, Roche). This compound has a chemical structure similar to nicotinic acid and is therapeutically indicated in functional and organic circulatory processes. We determine... |
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Effects of the lipolysis inhibiting agent beta-pyridylcarbinol (Ronicol) in acute myocardial ischaemia.
Acta Physiol. Hung. 74(2) , 169-74, (1989) The antilipolytic, nicotinic acid analogue beta-pyridylcarbinol (Ronicol) has previously been reported to decrease the free fatty acid (FFA) concentration of the arteria-blood, and to moderate the FFA-uptake and O2-consumption of the myocardium; on this basis... |