5-Hydroxyquinoline

5-Hydroxyquinoline Structure
5-Hydroxyquinoline structure
Common Name 5-Hydroxyquinoline
CAS Number 578-67-6 Molecular Weight 145.158
Density 1.3±0.1 g/cm3 Boiling Point 313.0±15.0 °C at 760 mmHg
Molecular Formula C9H7NO Melting Point 223-226 °C(lit.)
MSDS Chinese USA Flash Point 143.1±20.4 °C
Symbol GHS07
GHS07
Signal Word Warning

Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.

Bioorg. Med. Chem. Lett. 20 , 69-73, (2010)

A multiple linear regression QSAR model was developed based on a set of 61 compounds with internally consistent permeability data measured across Franz cell. The data was normalized using a mean permeability value of a reference compound, 3-isobutyl-1-methylx...

Infrared Spectrum and UV-Induced Photochemistry of Matrix-Isolated 5-Hydroxyquinoline.

J. Phys. Chem. A 119 , 6296-308, (2015)

The structure, infrared spectrum, and photochemistry of 5-hydroxyquinoline (5HQ) were studied by matrix isolation infrared spectroscopy, complemented by theoretical calculations performed at the DFT(B3LYP)/6-311++G(d,p) level of approximation. According to th...

Analysis of morphine in serum by high performance liquid chromatography with amperometric detection.

Ther. Drug Monit. 4(3) , 307-14, (1982)

In this report we describe a rapid and sensitive micromethod using high performance liquid chromatography (HPLC) with electrochemical detection (ED) to measure morphine concentration in serum or plasma. The separation of morphine and the internal standard 5-h...

Oxygen consumption in Plasmodium berghei-infected murine red cells: a direct spectrophotometric assay in intact erythrocytes.

Biochim. Biophys. Acta 886(3) , 319-26, (1986)

A spectrophotometric assay has been devised to measure oxygen consumption non-invasively in intact murine red cells parasitized by Plasmodium berghei. The method uses oxyhemoglobin in the erythrocytes both as a source of oxygen and as an indicator of oxygen c...

Quinoline: conversion to a mutagen by human and rodent liver.

J. Natl. Cancer Inst. 60(2) , 405-10, (1978)

Quinoline, a hepatocarcinogen in rats, and 23 quinoline derivatives were tested for mutagenic activity with the Ames Salmonella typhimurium assay. Quinoline, 5-hydroxyquinoline, and 8-hydroxyquinoline were mutagenic in strain TA 100 when Aroclor 1254-induced ...