UCL 2077
UCL 2077 structure
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Common Name | UCL 2077 | ||
|---|---|---|---|---|
| CAS Number | 918311-87-2 | Molecular Weight | 350.46 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H22N2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Ca2+-dependent and Na+-dependent K+ conductances contribute to a slow AHP in thalamic paraventricular nucleus neurons: a novel target for orexin receptors.
J. Neurophysiol. 104(4) , 2052-62, (2010) Thalamic paraventricular nucleus (PVT) neurons exhibit a postburst apamin-resistant slow afterhyperpolarization (sAHP) that is unique to midline thalamus, displays activity dependence, and is abolished in tetrodotoxin. Analysis of the underlying sI(AHP) confi... |
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Enhancement of hippocampal pyramidal cell excitability by the novel selective slow-afterhyperpolarization channel blocker 3-(triphenylmethylaminomethyl)pyridine (UCL2077).
Mol. Pharmacol. 70(5) , 1494-502, (2006) The slow afterhyperpolarization (sAHP) in hippocampal neurons has been implicated in learning and memory. However, its precise role in cell excitability and central nervous system function has not been explicitly tested for 2 reasons: 1) there are, at present... |
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