TUG-424

TUG-424 Structure
TUG-424 structure
Common Name TUG-424
CAS Number 1082058-99-8 Molecular Weight 264.318
Density 1.2±0.1 g/cm3 Boiling Point 448.1±38.0 °C at 760 mmHg
Molecular Formula C18H16O2 Melting Point N/A
MSDS Chinese USA Flash Point 205.9±21.4 °C
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

A potent class of GPR40 full agonists engages the enteroinsular axis to promote glucose control in rodents.

PLoS ONE 7 , e46300, (2012)

Type 2 diabetes is characterized by impaired glucose homeostasis due to defects in insulin secretion, insulin resistance and the incretin response. GPR40 (FFAR1 or FFA1) is a G-protein-coupled receptor (GPCR), primarily expressed in insulin-producing pancreat...