Glucose-6-phosphate dehydrogenase

Glucose-6-phosphate dehydrogenase Structure
Glucose-6-phosphate dehydrogenase structure
Common Name Glucose-6-phosphate dehydrogenase
CAS Number 9001-40-5 Molecular Weight 261.940
Density 2.0±0.1 g/cm3 Boiling Point 370.9±42.0 °C at 760 mmHg
Molecular Formula C5H10Br2O2 Melting Point N/A
MSDS USA Flash Point 178.1±27.9 °C

Initial characterization of the human central proteome.

BMC Syst. Biol. 5 , 17, (2011)

On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitously expressed in all human cells. Composition and properties...

A quantitative atlas of mitotic phosphorylation.

Proc. Natl. Acad. Sci. U. S. A. 105(31) , 10762-7, (2008)

The eukaryotic cell division cycle is characterized by a sequence of orderly and highly regulated events resulting in the duplication and separation of all cellular material into two newly formed daughter cells. Protein phosphorylation by cyclin-dependent kin...

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res. 14 , 2121-7, (2004)

The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for every human and mouse gene. The project initially used a r...

Lysine acetylation targets protein complexes and co-regulates major cellular functions.

Science 325(5942) , 834-40, (2009)

Lysine acetylation is a reversible posttranslational modification of proteins and plays a key role in regulating gene expression. Technological limitations have so far prevented a global analysis of lysine acetylation's cellular roles. We used high-resolution...

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

Anal. Chem. 81(11) , 4493-501, (2009)

The analysis of proteome-wide phosphorylation events is still a major analytical challenge because of the enormous complexity of protein phosphorylation networks. In this work, we evaluate the complementarity of Lys-N, Lys-C, and trypsin with regard to their ...

Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

Nat. Biotechnol. 21(5) , 566-9, (2003)

Current non-gel techniques for analyzing proteomes rely heavily on mass spectrometric analysis of enzymatically digested protein mixtures. Prior to analysis, a highly complex peptide mixture is either separated on a multidimensional chromatographic system or ...

Alterations of the redox state, pentose pathway and glutathione metabolism in an acute porphyria model. Their impact on heme pathway.

Exp. Biol. Med. (Maywood.) 238(2) , 133-43, (2013)

A classical acute porphyria model in rats consists of combined treatment with 2-allyl-2-isopropylacetamide (AIA) and 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC). The present work describes the effects of this treatment on the pentose phosphate (PP) pathwa...

Nicotinamide, a glucose-6-phosphate dehydrogenase non-competitive mixed inhibitor, modifies redox balance and lipid accumulation in 3T3-L1 cells.

Life Sci. 93(25-26) , 975-85, (2013)

Excessive energy uptake of dietary carbohydrates results in their storage as fat and requires glucose-6-phosphate dehydrogenase (G6PD)-mediated NADPH production. We sought to assess whether the nicotinamide-induced reduction of G6PD activity might modulate re...

[Carbohydrates metabolism disturbances when simulating prenatal alcohol intoxication].

Biomed. Khim. 59(5) , 523-9, (2013)

The influence of prenatal alcohol intoxication on carbohydrate metabolism markers has been investigated at different terms of postnatal offspring development (15, 30 and 60 days). Plasma glucose decreased as compared with the same in control group was detecte...

The DNA sequence of the human X chromosome.

Nature 434(7031) , 325-37, (2005)

The human X chromosome has a unique biology that was shaped by its evolution as the sex chromosome shared by males and females. We have determined 99.3% of the euchromatic sequence of the X chromosome. Our analysis illustrates the autosomal origin of the mamm...