Cephalothin Sodium

Cephalothin Sodium Structure
Cephalothin Sodium structure
Common Name Cephalothin Sodium
CAS Number 58-71-9 Molecular Weight 418.420
Density N/A Boiling Point 757.2ºC at 760 mmHg
Molecular Formula C16H15N2NaO6S2 Melting Point 240°C
MSDS Chinese USA Flash Point 411.8ºC
Symbol GHS08
GHS08
Signal Word Danger

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

J. Sci. Ind. Res. 65(10) , 808, (2006)

Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be tra...

Developing structure-activity relationships for the prediction of hepatotoxicity.

Chem. Res. Toxicol. 23 , 1215-22, (2010)

Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification o...

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug Metab. Dispos. 38 , 2302-8, (2010)

Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predictive in vivo, in vitro, and in silico models to identify comp...

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ...

Abiotrophia defectiva bleb-associated endophthalmitis confirmed with 16s ribosomal RNA sequencing.

J. Glaucoma 24(1) , 87-8, (2015)

One recognized complication of trabeculectomy with visually devastating potential is blebitis. We present a case of a 74-year-old woman with a culture and polymerase chain reaction-positive Abiotrophia defectiva bleb-associated endophthalmitis. Abiotrophia de...

Prevalence and antibiotic resistance of mastitis pathogens isolated from dairy herds transitioning to organic management.

J. Vet. Sci. 13(1) , 103-5, (2012)

Changes in udder health and antibiotic resistance of mastitis pathogens isolated from dairies upon conversion from conventional to organic management over a 3-year period was studied. Coagulase-negative staphylococci (CNS) were the most prevalent mastitis pat...

Oxacillin or cefalotin treatment of hospitalized children with cellulitis.

Jpn. J. Infect. Dis. 65(1) , 7-12, (2012)

Cellulitis is an important cause of hospitalization in pediatrics. Because Staphylococcus aureus is the main pathogen of cellulitis, medicinal therapeutics should take the changing resistance profile of this organism into consideration. The aim of this study ...

Neonatal Listeria-meningitis in San Luis, Argentina: a three-case report.

Rev. Argent. Microbiol. 43(1) , 45-7, (2011)

Between November 1996 and December 2006, two cases of early-onset and one case of late-onset neonatal listeriosis were reported in San Luis, Argentina. This article describes clinical and laboratory findings as well as treatment and outcome for newborns treat...

Reply: Protective effect of topical antibiotics in breast augmentation.

Plast. Reconstr. Surg. 131(1) , 115e, (2013)

Protective effect of topical antibiotics in breast augmentation.

Plast. Reconstr. Surg. 131(1) , 114e-5e, (2013)