Tazobactam Sodium Salt
Tazobactam Sodium Salt structure
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Common Name | Tazobactam Sodium Salt | ||
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| CAS Number | 89785-84-2 | Molecular Weight | 322.27300 | |
| Density | 1.92 g/cm3 | Boiling Point | 707.1ºC at 760 mmHg | |
| Molecular Formula | C10H11N4NaO5S | Melting Point | 140-147ºC | |
| MSDS | Chinese USA | Flash Point | 381.4ºC | |
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Quantification of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in serum using an isotope dilution UHPLC-MS/MS method with semi-automated sample preparation.
Clin. Chem. Lab Med. 53(5) , 781-91, (2015) Recent studies have demonstrated highly variable blood concentrations of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in critically ill patients with a high incidence of sub-therapeutic levels. Consequently, therapeutic drug moni... |
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DrugBank 3.0: a comprehensive resource for 'omics' research on drugs.
Nucleic Acids Res. 39 , D1035-41., (2011) DrugBank (http://www.drugbank.ca) is a richly annotated database of drug and drug target information. It contains extensive data on the nomenclature, ontology, chemistry, structure, function, action, pharmacology, pharmacokinetics, metabolism and pharmaceutic... |
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Variable susceptibility to piperacillin/tazobactam amongst Klebsiella spp. with extended-spectrum beta-lactamases.
J. Antimicrob. Chemother. 51 , 605-612, (2003) MICs of piperacillin/tazobactam are conventionally determined by varying the concentration of piperacillin in the presence of a fixed 4 mg/L tazobactam. When tested in this way, the MIC distribution for Klebsiella isolates with extended-spectrum beta-lactamas... |
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Inactivation of CMY-2 beta-lactamase by tazobactam: initial mass spectroscopic characterization.
Biochim. Biophys. Acta 1547 , 196, (2001) The CMY-2 beta-lactamase, a plasmid determined class C cephalosporinase, was shown to be susceptible to inhibition by tazobactam (K(i)=40 microM). The reaction product(s) of CMY-2 beta-lactamase with the beta-lactamase inhibitor tazobactam were analyzed by el... |
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In vitro antimicrobial activity of piperacillin/tazobactam in comparison with other broad-spectrum β-lactams. . Roland, R. K., et al.
J. Infect. Dis. 4 , 226, (2000)
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