Tazobactam Sodium Salt

Modify Date: 2024-01-02 21:39:06

Tazobactam Sodium Salt structure	Common Name	Tazobactam Sodium Salt
	CAS Number	89785-84-2	Molecular Weight	322.27300
	Density	1.92 g/cm3	Boiling Point	707.1ºC at 760 mmHg
	Molecular Formula	C₁₀H₁₁N₄NaO₅S	Melting Point	140-147ºC
	MSDS	Chinese USA	Flash Point	381.4ºC

Use of Tazobactam Sodium Salt

Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp..

Name	tazobactam sodium
Synonym	More Synonyms

Description	Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp..
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Giacobbe DR, et al. Ceftolozane/tazobactam: place in therapy. Expert Rev Anti Infect Ther. 2018;16(4):307‐320.

Density	1.92 g/cm3
Boiling Point	707.1ºC at 760 mmHg
Melting Point	140-147ºC
Molecular Formula	C₁₀H₁₁N₄NaO₅S
Molecular Weight	322.27300
Flash Point	381.4ºC
Exact Mass	322.03500
PSA	133.67000
Storage condition	Store at 0-5°C
Water Solubility	H2O: 50 mg/mL, clear, colorless

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XI0191500

CHEMICAL NAME :: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1- ylmethyl)-, 4,4-dioxide, sodium salt, (2S-(2-alpha,3-beta,5-alpha))-

CAS REGISTRY NUMBER :: 89785-84-2

LAST UPDATED :: 199409

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H11-N4-O5-S.Na

MOLECULAR WEIGHT :: 322.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 11,588,1986

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	XI0191500
HS Code	2934999090

2-METHANESULFON...

CAS#:89789-07-1

Tazobactam Sodi...

CAS#:89785-84-2

Literature: Journal of Medicinal Chemistry, , vol. 30, # 8 p. 1469 - 1474

Tazobactam

CAS#:89786-04-9

Piperacillin

CAS#:61477-96-1

Piperacillin Sodium

CAS#:59703-84-3

Tazobactam Sodi...

CAS#:89785-84-2

Literature: EP1759697 A1, ; Page/Page column 2-3 ;

Precursor 3
CAS#:89789-07-1 2-METHANESULFON... CAS#:89786-04-9 Tazobactam CAS#:61477-96-1 Piperacillin
DownStream 0

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Quantification of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in serum using an isotope dilution UHPLC-MS/MS method with semi-automated sample preparation.

Clin. Chem. Lab Med. 53(5) , 781-91, (2015)

Recent studies have demonstrated highly variable blood concentrations of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in critically ill patients with a high incidence of ...

DrugBank 3.0: a comprehensive resource for 'omics' research on drugs.

Nucleic Acids Res. 39 , D1035-41., (2011)

DrugBank (http://www.drugbank.ca) is a richly annotated database of drug and drug target information. It contains extensive data on the nomenclature, ontology, chemistry, structure, function, action, ...

Variable susceptibility to piperacillin/tazobactam amongst Klebsiella spp. with extended-spectrum beta-lactamases.

J. Antimicrob. Chemother. 51 , 605-612, (2003)

MICs of piperacillin/tazobactam are conventionally determined by varying the concentration of piperacillin in the presence of a fixed 4 mg/L tazobactam. When tested in this way, the MIC distribution f...

4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt, (2S,3S,5R)-

4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt, (2S,3S,5R)-

Sodium (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide

(2S,3S,5R)-3-méthyl-7-oxo-3-(1H-1,2,3-triazol-1-ylméthyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate-4,4-dioxyde de sodium

Tazobactam Sodium

MFCD00917472

Sodium (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate, 4,4-dioxide

[2S-(2a,3b,5a)]-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide sodium salt

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt, (2S,3S,5R)- (1:1)

Tazobactam sodium salt

CL 307,579

DC Chemicals Limited
China
Product Name: Tazobactam sodium
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Tazobactam sodium
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Tazobactam sodium
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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