ω-Agatoxin TK
ω-Agatoxin TK structure
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Common Name | ω-Agatoxin TK | ||
|---|---|---|---|---|
| CAS Number | 158484-42-5 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C215H337N65O70S10 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Controlling transgene expression in subcutaneous implants using a skin lotion containing the apple metabolite phloretin.
Proc. Natl. Acad. Sci. U. S. A. 106 , 10638-43, (2009) Adjustable control of therapeutic transgenes in engineered cell implants after transdermal and topical delivery of nontoxic trigger molecules would increase convenience, patient compliance, and elimination of hepatic first-pass effect in future therapies. Pse... |
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Calcium in sympathetic boutons of rat superior cervical ganglion during facilitation, augmentation and potentiation.
J. Auton. Nerv. Syst. 73 , 26-37, (1998) The sympathetic preganglionic nerve terminals of the rat superior cervical ganglion were loaded with the calcium indicator oregon green 488 BAPTA-1 to measure the change in calcium concentration in the terminal boutons, (delta[Ca2+]b) following short (1 or 5 ... |
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Serotonergic inhibition of the T-type and high voltage-activated Ca2+ currents in the primary sensory neurons of Xenopus larvae.
J. Neurosci. 17 , 6839-6849, (1997) The primary sensory Rohon-Beard (R-B) neurons of Xenopus larvae are highly analogous to the C fibers of the mammalian pain pathway. We explored the actions of 5-HT by studying the modulation of Ca2+ currents. In approximately 80% of the acutely isolated R-B n... |
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A novel type of calcium channel sensitive to omega-agatoxin-TK in cultured rat cerebral cortical neurons.
Brain Res. 756 , 225-230, (1997) We characterized the electrophysiological properties of calcium channels in cultured rat cerebral cortical neurons using omega-agatoxin-TK (omega-Aga-TK) by a patch-clamp technique. Two types of slowly inactivating calcium channels sensitive to omega-Aga-TK w... |
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Voltage-activated calcium channels involved in veratridine-evoked [3H]dopamine release in rat striatal slices.
Neuropharmacology 37 , 973-982, (1998) The present study explored the role of different sub-types of voltage-activated Ca2+ channels (VACCs) in mediating veratridine-evoked [3H]dopamine (DA) release from rat striatal slices. The release of [3H]DA evoked by veratridine (25 microM) decreased by 50.6... |
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A novel peptide from funnel web spider venom, omega-Aga-TK, selectively blocks, P-type calcium channels.
Biochem. Biophys. Res. Commun. 196 , 134-140, (1993) In the course of purification of omega-Aga-IVA, a specific P-type calcium channel blocker, from the venom of Agelenopsis aperta we discovered a novel peptide. This peptide, named omega-agatoxin Tsukuba (omega-Aga-TK), also blocked P-type channels and was twel... |
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Two types of calcium channels sensitive to omega-agatoxin- TK in cultured rat hippocampal neurones.
Neuroreport 6 , 1684-1688, (1995) We characterized the electrophysiological properties of calcium channels in cultured rat hippocampal neurones using omega-agatoxin-TK (omega-Aga-TK) and compared them with those of the P-type channel and the BI (alpha 1A) channel which resembles the Q-type ch... |