Sordarin sodium

Sordarin sodium Structure
Sordarin sodium structure
Common Name Sordarin sodium
CAS Number 463356-00-5 Molecular Weight 514.58
Density N/A Boiling Point N/A
Molecular Formula C27H39NaO8 Melting Point N/A
MSDS USA Flash Point N/A

Insights into diphthamide, key diphtheria toxin effector.

Toxins (Basel.) 5(5) , 958-68, (2013)

Diphtheria toxin (DT) inhibits eukaryotic translation elongation factor 2 (eEF2) by ADP-ribosylation in a fashion that requires diphthamide, a modified histidine residue on eEF2. In budding yeast, diphthamide formation involves seven genes, DPH1-DPH7. In an e...