CHLOROETHYLCLONIDINE DIHYDROCHLORIDE

CHLOROETHYLCLONIDINE DIHYDROCHLORIDE Structure
CHLOROETHYLCLONIDINE DIHYDROCHLORIDE structure
Common Name CHLOROETHYLCLONIDINE DIHYDROCHLORIDE
CAS Number 70107-07-2 Molecular Weight 408.582
Density N/A Boiling Point N/A
Molecular Formula C13H19Cl5N4 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Estradiol regulates responsiveness of the dorsal premammillary nucleus of the hypothalamus and affects fear- and anxiety-like behaviors in female rats.

Eur. J. Neurosci. 40(2) , 2344-51, (2014)

Research suggests a causal link between estrogens and mood. Here, we began by examining the effects of estradiol (E2 ) on rat innate and conditioned defensive behaviors in response to cat odor. Second, we utilized whole-cell patch clamp electrophysiological t...

Studies on some para-substituted clonidine derivatives that exhibit an alpha-adrenoceptor stimulant activity.

Br. J. Pharmacol. 71 , 5-9, (1980)

1 alpha-Adrenoceptor stimulant activity was determined for noradrenaline (NA), clonidine and a series of para-substituted derivatives of clonidine on rat aortic strips, a rat brain synaptosome preparation, and anaesthetized pithed rats. The effects on the blo...

Potent inhibitory action of chlorethylclonidine on the positive inotropic effect and phosphoinositide hydrolysis mediated via myocardial alpha 1-adrenoceptors in the rabbit ventricular myocardium.

Naunyn Schmiedebergs Arch. Pharmacol. 343 , 669, (1991)

The influence of the alpha 1b-adrenoceptor-selective antagonist chlorethylclonidine on the alpha 1-adrenergic positive inotropic effect and the phosphoinositide hydrolysis induced by phenylephrine was investigated in the rabbit ventricular myocardium. Pretrea...

Kinetics of alkylation of cloned rat alpha1-adrenoceptor subtypes by chloroethylclonidine.

Eur. J. Pharmacol. 347 , 319-327, (1998)

We quantified and compared the rates at which chloroethylclonidine (CEC) inactivated cloned rat alpha1A, alpha1B-, and alpha1D-adrenoceptors. Membranes from cells transfected with one of the three cloned alpha1-adrenoceptors were incubated for various interva...