2-Methylbenzoic acid
2-Methylbenzoic acid structure
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Common Name | 2-Methylbenzoic acid | ||
|---|---|---|---|---|
| CAS Number | 118-90-1 | Molecular Weight | 136.148 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 260.9±9.0 °C at 760 mmHg | |
| Molecular Formula | C8H8O2 | Melting Point | 103 °C | |
| MSDS | Chinese USA | Flash Point | 118.8±13.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Effect of aspirin treatment on the prevention of esophageal adenocarcinoma in a rat experimental model.
Oncol. Rep. 31(6) , 2785-91, (2014) Aspirin has been proposed in recent years as a candidate for chemoprevention of adenocarcinoma in patients with Barrett's esophagus. The aim of the present study was to evaluate the effect of acetylsalicylic acid (ASA) in an experimental model of esophageal a... |
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Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities.
PLoS ONE 9(6) , e98729, (2014) The ALKBH family of Fe(II) and 2-oxoglutarate dependent oxygenases comprises enzymes that display sequence homology to AlkB from E. coli, a DNA repair enzyme that uses an oxidative mechanism to dealkylate methyl and etheno adducts on the nucleobases. Humans h... |
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Oxidation of tolualdehydes to toluic acids catalyzed by cytochrome P450-dependent aldehyde oxygenase in the mouse liver.
Drug Metab. Dispos. 23(2) , 261-5, (1995) Mouse hepatic microsomal enzymes catalyzed the oxidation of o-, m-, and p-tolualdehydes, intermediate metabolites of xylene, to the corresponding toluic acids. Cofactor requirement for the catalytic activity indicates that the microsomes contain NAD- and NADP... |
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Effects of the headspace gas composition on anaerobic biotransformation of o-, m-, and p-toluic acid in sediment slurries.
J. Environ. Sci. Health. A. Tox. Hazard. Subst. Environ. Eng. 38(6) , 1099-113, (2003) Composition of the headspace gas affected the biotransformation pattern of toluic acid isomers in anoxic sediment slurries. Under an N2 atmosphere, o- and m-, and p-toluic acid (20-25 mg L(-1)) were biotransformed in 100 days, 77 days, and 148 days, respectiv... |
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Dual-opposite injection electrokinetic chromatography for the unbiased, simultaneous separation of cationic and anionic compounds.
Electrophoresis 21(10) , 1997-2009, (2000) The concept of dual opposite injection in capillary electrophoresis (DOI-CE) for the simultaneous separation, under conditions of suppressed electroosmotic flow, of anionic and cationic compounds with no bias in resolution and analysis time, is extended to a ... |
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The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage.
Nucleic Acids Res. 40 , 6620-31, (2012) The Escherichia coli AlkB protein (EcAlkB) is a DNA repair enzyme which reverses methylation damage such as 1-methyladenine (1-meA) and 3-methylcytosine (3-meC). The mammalian AlkB homologues ALKBH2 and ALKBH3 display EcAlkB-like repair activity in vitro, but... |
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Bioinformatics and functional analysis define four distinct groups of AlkB DNA-dioxygenases in bacteria.
Nucleic Acids Res. 37 , 7124-36, (2009) The iron(II)- and 2-oxoglutarate (2OG)-dependent dioxygenase AlkB from Escherichia coli (EcAlkB) repairs alkylation damage in DNA by direct reversal. EcAlkB substrates include methylated bases, such as 1-methyladenine (m(1)A) and 3-methylcytosine (m(3)C), as ... |
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Novel AlkB dioxygenases--alternative models for in silico and in vivo studies.
PLoS ONE 7 , e30588, (2012) ALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic activity of alkylating agents, chemicals significantly contributing to tu... |
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The pH and anion effects on the heterogeneous photocatalytic degradation of o-methylbenzoic acid in TiO2 aqueous suspension.
Chemosphere 40(4) , 389-94, (2000) This investigation used UV light of 365 nm and titanium dioxide in aqueous suspension to study the photocatalytic reaction of o-methylbenzoic acid under the influence of pH values, anion additives and the varieties of titanium dioxide. From experimental resul... |