piperazine citrate hydrate
piperazine citrate hydrate structure
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Common Name | piperazine citrate hydrate | ||
|---|---|---|---|---|
| CAS Number | 41372-10-5 | Molecular Weight | 660.669 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H56N6O19 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Endogenous formation of N-nitrosamines from piperazine and their urinary excretion following antihelmintic treatment with piperazine citrate.
Carcinogenesis 12(9) , 1595-9, (1991) Antihelmintic treatment with piperazine (1,4-diazacyclohexane) for microfilarie parasitism results in the endogenous formation of piperazine-derived N-nitrosamines. The urinary excretion of these N-nitrosamines was determined by biochemical monitoring of 14 p... |
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Some effects of piperazine citrate on skeletal muscle and central nervous system.
Arch. Int. Pharmacodyn. Ther. 290(1) , 104-16, (1987) In the frog rectus abdominis and rat phrenic nerve-diaphragm preparations, piperazine citrate was shown to have some neuromuscular blocking activity. In the rat, d-tubocurarine was 500 times more potent than piperazine. This neuromuscular blocking effect of p... |
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Treatment of helminthic diseases.
Am. Fam. Physician 32(3) , 182-8, (1985)
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Synthesis and biological evaluation of novel benzothiazole clubbed fluoroquinolone derivatives.
J. Enzyme Inhib. Med. Chem. 28(1) , 1-10, (2013) In the present investigation, synthesis and anti-bacterial, analgesic and anthelmintic evaluation of a novel series of fluoroquinolone derivatives clubbed with benzothiazole moeity has been described. The synthesized compounds were characterised by spectral a... |
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Management of intestinal obstruction caused by ascariasis.
J. Pediatr. Surg. 32(4) , 585-7, (1997) A retrospective clinical study to evaluate the effects of paralyzing vermifuges on the course of intestinal obstructions complicating ascariasis was performed. Forty-two patients, 26 patients with partial and 16 patients with complete intestinal obstructions,... |
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Occupational asthma due to piperazine citrate.
J. Investig. Allergol. Clin. Immunol. 16(2) , 138-9, (2006) Piperazine is a secondary heterocyclic amine that may give rise to occupational asthma of uncertain mechanism.We report on a 42-year-old woman, a process operator in a chemical factory, who developed work-related symptoms of rhinitis and asthma upon exposure ... |
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Hypokalemic paralysis following severe vomiting in a child with intestinal obstruction due to round worms.
J. Trop. Pediatr. 56(1) , 63-4, (2010) Ascariasis is one of the most common helminthic infestations in humans. Massive infestation can give rise to serious complications such as intestinal obstruction. We present a 4-year-old boy, who presented with acute flaccid quadriparesis due to the hypokalem... |
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Impact of subchronic administration of piperazine citrate on the electrocardiogram of the rat.
Am. J. Ther. 19(2) , 81-7, (2012) The effect of piperazine citrate on the electrocardiogram of the rat after treatment with piperazine citrate at 30, 60, and 100 mg/kg body weight for 16 weeks was investigated. The results were compared with a control group. There was prolongation of P-R, Q-T... |
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Piperazine toxicity in a kitten.
Vet. Rec. 119(25-26) , 635, (1986)
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Piperazine toxicity in Afghan puppies.
Vet. Rec. 120(13) , 310, (1987)
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