methylprednisolone acetate
methylprednisolone acetate structure
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Common Name | methylprednisolone acetate | ||
|---|---|---|---|---|
| CAS Number | 53-36-1 | Molecular Weight | 416.507 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 582.5±50.0 °C at 760 mmHg | |
| Molecular Formula | C24H32O6 | Melting Point | 206ºC | |
| MSDS | Chinese USA | Flash Point | 196.5±23.6 °C | |
| Symbol |
GHS08 |
Signal Word | Warning | |
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Achyranthes bidentata extract exerts osteoprotective effects on steroid-induced osteonecrosis of the femoral head in rats by regulating RANKL/RANK/OPG signaling.
J. Transl. Med. 12 , 334, (2014) Steroid-induced osteonecrosis of the femoral head (steroid-induced ONFH) presents great challenges due to the various effects of steroids on multi-system pathways involved into osteoblast differentiation, osteoblast and osteoclast apoptosis, lipid metabolism,... |
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Cholesterol- and lanolin-rich diets may protect against steroid-induced osteonecrosis in rabbits.
Acta Orthop. 84(6) , 593-7, (2013) It remains controversial how hypercholesterolemia influences the development of steroid-induced osteonecrosis (ON). We investigated the role of hypercholesterolemia induced by a cholesterol-rich diet on the development of ON in rabbits.40 adult male Japanese ... |
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Notes from the field: Department of Defense response to a multistate outbreak of fungal meningitis--United States, October 2012.
MMWR Morb. Mortal. Wkly. Rep. 62(38) , 800-1, (2013) On October 1, 2012, the Department of Defense (DoD) learned of a multistate outbreak of fungal meningitis in persons who received injections of methylprednisolone acetate (MPA) from a single compounding pharmacy. Ten patients with fungal meningitis after epid... |
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Relapse of fungal meningitis associated with contaminated methylprednisolone.
N. Engl. J. Med. 368(26) , 2535-6, (2013)
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The effects of glucocorticoids on neuropathic pain: a review with emphasis on intrathecal methylprednisolone acetate delivery.
Anesth. Analg. 118(5) , 1097-112, (2014) Methylprednisolone acetate (MPA) has a long history of use in the treatment of sciatic pain and other neuropathic pain syndromes. In several of these syndromes, MPA is administered in the epidural space. On a limited basis, MPA has also been injected intrathe... |
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Fungal meningitis outbreak affects over 700.
Lancet Neurol. 12(5) , 429-30, (2013)
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Spinal and paraspinal infections associated with contaminated methylprednisolone acetate injections - Michigan, 2012-2013.
MMWR Morb. Mortal. Wkly. Rep. 62(19) , 377-81, (2013) As of May 6, 2013, Michigan had reported 167 (52%) of the 320 paraspinal or spinal infections without meningitis associated with the 2012-2013 fungal meningitis outbreak nationally. Although the index patient had a laboratory-confirmed Aspergillus fumigatus i... |
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Epidural administration of methylprednisolone acetate preserved with benzyl alcohol.
Ann. Pharmacother. 28(1) , 59-60, (1994)
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Delineating the role of multiple intraarticular corticosteroid injections in the management of juvenile idiopathic arthritis in the biologic era.
Arthritis Care Res. (Hoboken.) 65(7) , 1112-20, (2013) To investigate the outcome and predicting factors of multiple intraarticular corticosteroid (IAC) injections in children with juvenile idiopathic arthritis (JIA).The clinical charts of patients who received their first IAC injection in ≥3 joints between Janua... |
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The effects of corticosteroid injection versus local anesthetic injection in the treatment of lateral epicondylitis: a randomized single-blinded clinical trial.
Arch. Orthop. Trauma Surg. 133(6) , 757-63, (2013) This study seeks to compare two treatment methods of lateral epicondylitis: corticosteroid injection (CSI) and a local anesthetic injection (LAI).In this single-blinded randomized clinical trial, 138 patients with the diagnosis of lateral epicondylitis were a... |