Chloral hydrate

Chloral hydrate Structure
Chloral hydrate structure
Common Name Chloral hydrate
CAS Number 302-17-0 Molecular Weight 165.403
Density 1.8±0.1 g/cm3 Boiling Point 96.3±0.0 °C at 760 mmHg
Molecular Formula C2H3Cl3O2 Melting Point 57 °C(lit.)
MSDS Chinese USA Flash Point 57.3±25.9 °C
Symbol GHS07
GHS07
Signal Word Warning

The matrix polysaccharide (1;3,1;4)-β-D-glucan is involved in silicon-dependent strengthening of rice cell wall.

Plant Cell Physiol. 56(2) , 268-76, (2015)

Poales [represented by rice (Oryza sativa L.)] in angiosperms and Equisetum (horsetails) in Pteridophytes are two major groups of heavy silicon (Si) accumulators. In rice, Si is polymerized preferentially in the epidermal cell wall, forming Si-cuticle double ...

Appetitive cue-evoked ERK signaling in the nucleus accumbens requires NMDA and D1 dopamine receptor activation and regulates CREB phosphorylation.

Learn. Mem. 21(11) , 606-15, (2014)

Conditioned stimuli (CS) can modulate reward-seeking behavior. This modulatory effect can be maladaptive and has been implicated in excessive reward seeking and relapse to drug addiction. We previously demonstrated that exposure to an appetitive CS causes an ...

Ciliary abnormalities in senescent human fibroblasts impair proliferative capacity.

Cell Cycle 13(17) , 2773-9, (2014)

Somatic cells senesce in culture after a finite number of divisions indefinitely arresting their proliferation. DNA damage and senescence increase the cellular number of centrosomes, the 2 microtubule organizing centers that ensure bipolar mitotic spindles. C...

The CRE1 cytokinin pathway is differentially recruited depending on Medicago truncatula root environments and negatively regulates resistance to a pathogen.

PLoS ONE 10(1) , e0116819, (2015)

Cytokinins are phytohormones that regulate many developmental and environmental responses. The Medicago truncatula cytokinin receptor MtCRE1 (Cytokinin Response 1) is required for the nitrogen-fixing symbiosis with rhizobia. As several cytokinin signaling gen...

bFGF attenuates endoplasmic reticulum stress and mitochondrial injury on myocardial ischaemia/reperfusion via activation of PI3K/Akt/ERK1/2 pathway.

J. Cell. Mol. Med. 19(3) , 595-607, (2015)

Extensive research focused on finding effective strategies to prevent or improve recovery from myocardial ischaemia/reperfusion (I/R) injury. Basic fibroblast growth factor (bFGF) has been shown to have therapeutic potential in some heart disorders, including...

Cerebral cortex, hippocampus, striatum and cerebellum show differential susceptibility to quinolinic acid-induced oxidative stress.

Neurol. Sci. 36 , 1449-56, (2015)

Quinolinic acid (QA) is a NMDA receptor agonist implicated in pathological conditions, such as neurodegenerative diseases and epilepsy. Time-course responses of different brain regions after QA i.c.v. infusion are not known. We aimed to investigate the time-c...

Analysis of the direct injury effector of oligodendroglia cells or myelin sheath in an experimental allergic encephalomyelitis model induced by the MOG35-55 peptide.

Mol. Med. Report. 12 , 7425-32, (2015)

The aim of the present study was to investigate the possible role of cytotoxic T lymphocytes (CTL) and mononuclear macrophages in the pathogenic processes of experimental animals. To construct a chronic experimental allergic encephalomyelitis (EAE) model, an ...

Dopamine receptors and the persistent neurovascular dysregulation induced by methamphetamine self-administration in rats.

J. Pharmacol. Exp. Ther. 351(2) , 432-9, (2014)

Recently abstinent methamphetamine (Meth) abusers showed neurovascular dysregulation within the striatum. The factors that contribute to this dysregulation and the persistence of these effects are unclear. The current study addressed these knowledge gaps. Fir...

Propofol ameliorates calpain-induced collapsin response mediator protein-2 proteolysis in traumatic brain injury in rats.

Chin. Med. J. 128(7) , 919-27, (2015)

Collapsin response mediator protein-2 (CRMP2), a multifunctional cytosolic protein highly expressed in the brain, is degraded by calpain following traumatic brain injury (TBI), possibly inhibiting posttraumatic neurite regeneration. Lipid peroxidation (LP) is...

Magnesium modulates the expression levels of calcification-associated factors to inhibit calcification in a time-dependent manner.

Exp. Ther. Med. 9(3) , 1028-1034, (2015)

Vascular calcification, a common complication in patients with chronic kidney disease, involves a variety of mechanisms associated with the regulation of calcification-associated factors. Previous clinical studies have indicated that magnesium is involved in ...